SCARB1 and KRTAP5-9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SCARB1	KRTAP5-9
Gene Name		scavenger receptor class B, member 1	keratin associated protein 5-9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Caveola Cell Surface Endocytic Vesicle Membrane Microvillus Membrane Extracellular Vesicular Exosome	Keratin Filament
	Molecular Function	Lipopolysaccharide Binding Phosphatidylserine Binding Lipopolysaccharide Receptor Activity Transporter Activity Protein Binding 1-phosphatidylinositol Binding High-density Lipoprotein Particle Binding Low-density Lipoprotein Particle Binding Apolipoprotein Binding Apolipoprotein A-I Binding Protein Homodimerization Activity High-density Lipoprotein Particle Receptor Activity	Protein Binding
	Biological Process	Endothelial Cell Proliferation Androgen Biosynthetic Process Cholesterol Catabolic Process Receptor-mediated Endocytosis Cell Adhesion Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Cholesterol Storage Regulation Of Phosphatidylcholine Catabolic Process Phospholipid Transport Lipopolysaccharide Transport Viral Process Lipopolysaccharide-mediated Signaling Pathway Detection Of Lipopolysaccharide Cholesterol Efflux High-density Lipoprotein Particle Remodeling Low-density Lipoprotein Particle Clearance High-density Lipoprotein Particle Clearance Wound Healing Lipoprotein Metabolic Process Cholesterol Homeostasis Blood Vessel Endothelial Cell Migration Recognition Of Apoptotic Cell Reverse Cholesterol Transport Small Molecule Metabolic Process Adhesion Of Symbiont To Host Regulation Of Phagocytosis Positive Regulation Of Nitric-oxide Synthase Activity Triglyceride Homeostasis Cholesterol Import	Epidermis Development
Pathways
Drugs		Phosphatidylserine
Diseases
GWAS		HDL cholesterol ( 20686565) Lipoprotein-associated phospholipase A2 activity and mass ( 23118302 20442857) Renal cell carcinoma ( 21131975) Vitamin E levels ( 21729881)
Protein-Protein Interactions		7 interactors: APOA1 APOA2 APOE KRTAP10-9 KRTAP5-9 PDZK1 PEX5	103 interactors: ADAMTSL4 ALPP ATG9A BEX2 BMP7 C10orf62 C11orf87 C19orf66 CARKD CATSPER1 CHIC2 CHRD CKS1B CNNM3 COMT CRCT1 CTSZ CXCL16 DHRS1 DMRT3 DOCK2 FAH FAM124B FAM161A FAM74A4 FAM76B GLRX3 GNE HOXA1 HOXB9 HPCAL1 HSPD1 JOSD1 KLHL38 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE3C LCE3E LCE4A LY6H MAPKBP1 MEOX2 NCLN NLK NMU NOTCH2NL NPBWR2 NPDC1 NTM NTN4 NUFIP2 OTX1 P2RX4 PCSK5 PFKL PGLS POM121L8P PRKAB2 PSMA1 PTPMT1 PVRL2 RAMP3 RGS20 RNF111 SCARB1 SDC3 SDCBP SLC22A23 SLC25A10 SMCP SPINK2 SPRY2 TBC1D10C TBC1D16 TCEA2 TCEANC TOMM22 TYRO3 WDYHV1 YIPF3 ZBTB24 ZFYVE21 ZNF124 ZNF266 ZNF417 ZNF439 ZNF581 ZNF587
Entrez ID		949	3846
HPRD ID		03024	01008
Ensembl ID		ENSG00000073060	ENSG00000254997
Uniprot IDs		B3KW46 B4DZ71 B4E3I1 B7ZKQ9 F8W8N0 Q8WTV0	P26371
PDB IDs
Enriched GO Terms of Interacting Partners?		High-density Lipoprotein Particle Clearance Positive Regulation Of Cholesterol Esterification High-density Lipoprotein Particle Assembly Regulation Of Cholesterol Esterification Phospholipid Efflux High-density Lipoprotein Particle Remodeling Protein-lipid Complex Assembly Reverse Cholesterol Transport Plasma Lipoprotein Particle Remodeling Positive Regulation Of Steroid Metabolic Process Cholesterol Efflux Plasma Lipoprotein Particle Clearance Regulation Of Cholesterol Transport Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Regulation Of Plasma Lipoprotein Particle Levels Cholesterol Transport Sterol Transport Cholesterol Homeostasis Sterol Homeostasis Phototransduction, Visible Light Retinoid Metabolic Process Regulation Of Intestinal Cholesterol Absorption Protein Oxidation Diterpenoid Metabolic Process Detection Of Visible Light Regulation Of Lipid Transport Phospholipid Transport Negative Regulation Of Cytokine Secretion Involved In Immune Response Phototransduction Regulation Of Steroid Metabolic Process Organic Anion Transport Detection Of Light Stimulus Peptidyl-methionine Modification Peripheral Nervous System Axon Regeneration Triglyceride-rich Lipoprotein Particle Remodeling Cholesterol Metabolic Process Lipid Homeostasis Low-density Lipoprotein Particle Remodeling Isoprenoid Metabolic Process Negative Regulation Of Cholesterol Transport Sterol Metabolic Process Cellular Lipid Catabolic Process Regulation Of Cytokine Secretion Involved In Immune Response Lipoprotein Metabolic Process Detection Of Abiotic Stimulus Negative Regulation Of Lipase Activity Anion Transport Negative Regulation Of Lipid Transport Phosphatidylcholine Biosynthetic Process Acylglycerol Catabolic Process	Keratinization Keratinocyte Differentiation Pattern Specification Process Epidermal Cell Differentiation Developmental Process Positive Regulation Of Immune Response To Tumor Cell Adhesion Of Symbiont To Host Locomotion Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Muscle Hypertrophy Organ Development Cell Recognition Skin Development Multicellular Organismal Development Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Anterior/posterior Pattern Specification Cell Differentiation System Development Epidermis Development Transcription, DNA-templated
Tagcloud ?		abca1 alfalfa aragonesa breed concentrate contrary dams finishing grazed grazing indoors lambs lengths lpl lt ppara pparg rasa sf slaughtering srebp1 subcutaneous supplemented thoracis tocopherol tocopheryl ve10d ve20d ve30d
Tagcloud (Difference) ?		abca1 alfalfa aragonesa breed concentrate contrary dams finishing grazed grazing indoors lambs lengths lpl lt ppara pparg rasa sf slaughtering srebp1 subcutaneous supplemented thoracis tocopherol tocopheryl ve10d ve20d ve30d
Tagcloud (Intersection) ?