PGS1 and PDLIM1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PGS1	PDLIM1
Gene Name		phosphatidylglycerophosphate synthase 1	PDZ and LIM domain 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Endoplasmic Reticulum	Transcription Factor Complex Cytoplasm Cytoskeleton Focal Adhesion
	Molecular Function	Calcium Ion Binding ATP Binding CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase Activity	Transcription Coactivator Activity Zinc Ion Binding
	Biological Process	Phospholipid Metabolic Process Phosphatidylglycerol Biosynthetic Process Cardiolipin Biosynthetic Process Small Molecule Metabolic Process Diacylglycerol Metabolic Process Glycerophospholipid Biosynthetic Process	Response To Hypoxia Regulation Of Transcription, DNA-templated Response To Oxidative Stress
Pathways		Metabolism of lipids and lipoproteins Synthesis of PG Phospholipid metabolism Glycerophospholipid biosynthesis
Drugs
Diseases
GWAS		HDL cholesterol ( 20686565)
Protein-Protein Interactions		2 interactors: GABARAP PDLIM1	13 interactors: ACTN1 ACTN2 ACTN4 AGK GFAP MAPK6 PGS1 PITX2 RLIM RPS6KA5 STK35 SUPT4H1 VIM
Entrez ID		9489	9124
HPRD ID		17841	09326
Ensembl ID		ENSG00000087157	ENSG00000107438
Uniprot IDs		Q32NB8	O00151
PDB IDs			1X62 2PKT
Enriched GO Terms of Interacting Partners?			Protein Localization To Tight Junction Bergmann Glial Cell Differentiation Protein Localization To Cell Junction Platelet Degranulation Intermediate Filament Organization Actin Crosslink Formation Astrocyte Development Actin-myosin Filament Sliding Focal Adhesion Assembly Muscle Filament Sliding Platelet Activation Cell Junction Assembly Cell-cell Junction Organization Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Intermediate Filament-based Process Actin-mediated Cell Contraction Tight Junction Assembly Adherens Junction Assembly Actin Filament-based Process Positive Regulation Of Ion Transmembrane Transporter Activity Cell-substrate Junction Assembly Response To Wounding Positive Regulation Of Transporter Activity Actin Filament Bundle Assembly Actin Filament-based Movement Histone H2A-S1 Phosphorylation Subthalamic Nucleus Development Prolactin Secreting Cell Differentiation Random Inactivation Of X Chromosome Positive Regulation Of Schwann Cell Proliferation Superior Vena Cava Morphogenesis Apical Junction Assembly Exocytosis Positive Regulation Of Ion Transmembrane Transport Adherens Junction Organization Cell Proliferation Involved In Outflow Tract Morphogenesis Subthalamus Development Left Lung Morphogenesis Pulmonary Vein Morphogenesis Blood Coagulation Glial Cell Development Hemostasis Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Extraocular Skeletal Muscle Development Pulmonary Myocardium Development Positive Regulation Of Pinocytosis Left Lung Development Cell-cell Junction Assembly Negative Regulation Of Neuron Projection Development
Tagcloud ?		aa adducts arachidonic bioactive bioactivities butyl centered cox cyclooxygenase dgla dihomo exclusively linolenic metabolizes nitrone omega oxygenation peroxidation pggs pgs2 pobn polyunsaturated prostaglandins pyridyl radicals tert viewed z
Tagcloud (Difference) ?		aa adducts arachidonic bioactive bioactivities butyl centered cox cyclooxygenase dgla dihomo exclusively linolenic metabolizes nitrone omega oxygenation peroxidation pggs pgs2 pobn polyunsaturated prostaglandins pyridyl radicals tert viewed z
Tagcloud (Intersection) ?