LGALS3BP and SIGLEC11

Number of citations of the paper that reports this interaction (PubMedID 25320078)
66

Data Source:
BioGRID (pull down)

		LGALS3BP	SIGLEC11
Description		galectin 3 binding protein	sialic acid binding Ig like lectin 11
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane Extracellular Matrix Platelet Dense Granule Lumen Extracellular Exosome Blood Microparticle	Plasma Membrane Membrane
	Molecular Function	Scavenger Receptor Activity Protein Binding	Phosphatase Binding Carbohydrate Binding Sialic Acid Binding
	Biological Process	Cellular Defense Response Cell Adhesion Signal Transduction Vesicle-mediated Transport	Cell Adhesion
Pathways		Platelet degranulation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Lung cancer in never smokers ( 28604730)
Interacting Genes		24 interacting genes: CD14 COL5A1 COL6A1 FBXO7 FN1 GALNT6 HSP90AA1 ITGA5 ITGA6 ITGAV ITGB1 LGALS1 LGALS3 NID1 PPIC SELE SIGLEC10 SIGLEC11 SIGLEC5 SIGLEC6 SIGLEC7 SIGLEC9 WNT4 XRN1	3 interacting genes: LGALS3BP PTPN11 PTPN6
Entrez ID		3959	114132
HPRD ID		02796	06196
Ensembl ID		ENSG00000108679	ENSG00000161640
Uniprot IDs		Q08380	Q96RL6
PDB IDs		1BY2 6GFB
Enriched GO Terms of Interacting Partners?		Cell Adhesion Sialic Acid Binding Carbohydrate Binding Wound Healing, Spreading Of Epidermal Cells Cell-matrix Adhesion Laminin Binding Integrin Complex Cell-substrate Adhesion Wound Healing, Spreading Of Cells Response To Muscle Activity Endodermal Cell Differentiation Integrin-mediated Signaling Pathway Proteoglycan Binding Regulation Of Cellular Component Organization Plasma Membrane Extracellular Matrix Cell Surface Cell Migration Integrin Binding Integrin Alpha6-beta1 Complex Integrin Alpha5-beta1 Complex Integrin Alphav-beta1 Complex Response To Activity Positive Regulation Of Cell Adhesion Cell Motility Basement Membrane Positive Regulation Of Cell Migration Regulation Of Locomotion Cell Adhesion Mediated By Integrin Regulation Of Cell Adhesion Secretory Granule Membrane Positive Regulation Of Cell Motility Calcium-independent Cell-matrix Adhesion Positive Regulation Of Locomotion Basement Membrane Organization Negative Regulation Of Apoptotic Signaling Pathway Heterotypic Cell-cell Adhesion Neuregulin Binding C-X3-C Chemokine Binding Cell-substrate Junction Assembly Cell-substrate Junction Organization Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Dendritic Cell Differentiation Signaling Receptor Activity Regulation Of Cell Migration Cell-cell Adhesion Mediated By Integrin Extracellular Exosome Endoplasmic Reticulum Lumen Extracellular Region Regulation Of Cell Motility	Non-membrane Spanning Protein Tyrosine Phosphatase Activity Negative Regulation Of Neutrophil Activation Regulation Of Neutrophil Activation Neutrophil Activation Involved In Immune Response Peptidyl-tyrosine Dephosphorylation Platelet Formation Megakaryocyte Development Regulation Of Lipopolysaccharide-mediated Signaling Pathway Neutrophil Activation Regulation Of Type I Interferon-mediated Signaling Pathway Phosphotyrosine Residue Binding T Cell Costimulation Regulation Of Cell Adhesion Mediated By Integrin Myeloid Cell Development Negative Regulation Of T Cell Proliferation Protein Dephosphorylation Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Cell Adhesion Molecule Binding Protein Tyrosine Phosphatase Activity Negative Regulation Of Leukocyte Proliferation Dephosphorylation Myeloid Leukocyte Activation Epididymis Development Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Phosphoprotein Phosphatase Activity Negative Regulation Of T Cell Activation Leukocyte Activation Involved In Immune Response Negative Regulation Of Leukocyte Cell-cell Adhesion Cell Activation Involved In Immune Response Negative Regulation Of Lymphocyte Activation Regulation Of Tumor Necrosis Factor Production Hemopoiesis Regulation Of Cytokine-mediated Signaling Pathway Regulation Of T Cell Proliferation Intestinal Epithelial Cell Migration Negative Regulation Of Leukocyte Activation Negative Regulation Of Cell-cell Adhesion Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Cell Activation Cerebellar Cortex Formation Regulation Of Mononuclear Cell Proliferation Myeloid Cell Differentiation Positive Regulation Of T Cell Activation Negative Regulation Of Mast Cell Activation Involved In Immune Response Negative Regulation Of Glucocorticoid Secretion Regulation Of Leukocyte Proliferation Regulation Of ERK1 And ERK2 Cascade CD27 Signaling Pathway
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