LGALS3BP and SIGLEC5

Number of citations: 66 (PubMedID 25320078)
Data Source: BioGRID (pull down)

		LGALS3BP	SIGLEC5
Name		galectin 3 binding protein	sialic acid binding Ig like lectin 5
Structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane Extracellular Matrix Platelet Dense Granule Lumen Extracellular Exosome Blood Microparticle	Plasma Membrane Membrane Secretory Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Scavenger Receptor Activity Protein Binding	Protein Binding Carbohydrate Binding Sialic Acid Binding
	Biological Process	Cellular Defense Response Cell Adhesion Signal Transduction Vesicle-mediated Transport	Cell Adhesion
Pathways		Platelet degranulation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation
GWAS		Blood protein levels ( 30072576 )	Addison's disease ( 33574239 ) Aggressive periodontitis ( 28449029 ) Eosinophil count ( 32888494 ) Eosinophil percentage of white cells ( 32888494 ) Leprosy ( 25642632 ) Lymphocyte count ( 27863252 32888494 ) Mean corpuscular hemoglobin concentration ( 32888494 ) Mean spheric corpuscular volume ( 32888494 ) Monocyte count ( 32888494 ) Neutrophil percentage of white cells ( 32888494 ) Periodontitis ( 30218097 ) Platelet distribution width ( 32888494 ) Systemic lupus erythematosus ( 33272962 )
Interacting Genes		24 interacting genes: CD14 COL5A1 COL6A1 FBXO7 FN1 GALNT6 HSP90AA1 ITGA5 ITGA6 ITGAV ITGB1 LGALS1 LGALS3 NID1 PPIC SELE SIGLEC10 SIGLEC11 SIGLEC5 SIGLEC6 SIGLEC7 SIGLEC9 WNT4 XRN1	5 interacting genes: LGALS3BP NAPB SLC7A8 TRIP13 VAC14
Entrez ID		3959	8778
HPRD ID		02796	05011
Ensembl ID		ENSG00000108679	ENSG00000268500
Uniprot IDs		Q08380	O15389
PDB IDs		1BY2 6GFB	2ZG1 2ZG2 2ZG3
GO Terms Enriched among Interactors		Cell Adhesion Sialic Acid Binding Carbohydrate Binding Wound Healing, Spreading Of Epidermal Cells Cell-matrix Adhesion Laminin Binding Integrin Complex Cell-substrate Adhesion Wound Healing, Spreading Of Cells Response To Muscle Activity Endodermal Cell Differentiation Integrin-mediated Signaling Pathway Proteoglycan Binding Regulation Of Cellular Component Organization Plasma Membrane Extracellular Matrix Cell Surface Cell Migration Integrin Binding Integrin Alpha6-beta1 Complex Integrin Alpha5-beta1 Complex Integrin Alphav-beta1 Complex Response To Activity Positive Regulation Of Cell Adhesion Cell Motility Basement Membrane Positive Regulation Of Cell Migration Regulation Of Locomotion Cell Adhesion Mediated By Integrin Regulation Of Cell Adhesion Secretory Granule Membrane Positive Regulation Of Cell Motility Calcium-independent Cell-matrix Adhesion Positive Regulation Of Locomotion Basement Membrane Organization Negative Regulation Of Apoptotic Signaling Pathway Heterotypic Cell-cell Adhesion Neuregulin Binding C-X3-C Chemokine Binding Cell-substrate Junction Assembly Cell-substrate Junction Organization Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Dendritic Cell Differentiation Signaling Receptor Activity Regulation Of Cell Migration Cell-cell Adhesion Mediated By Integrin Extracellular Exosome Endoplasmic Reticulum Lumen Extracellular Region Regulation Of Cell Motility	Female Meiosis I Meiotic Recombination Checkpoint Signaling Meiotic Cell Cycle Checkpoint Signaling L-alanine Transport Tryptophan Transport Proline Transmembrane Transport L-alanine Transmembrane Transport L-leucine Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity L-leucine Import Across Plasma Membrane Glycine Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-alanine Import Across Plasma Membrane Thyroid Hormone Transmembrane Transporter Activity Valine Transport PAS Complex Presynaptic Endosome Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Soluble NSF Attachment Protein Activity SNARE Complex Disassembly Negative Regulation Of Meiotic Nuclear Division Branched-chain Amino Acid Transport Organic Cation Transmembrane Transporter Activity Aromatic Amino Acid Transport L-leucine Transport Thyroid Hormone Transport Regulation Of Synaptic Vesicle Priming Glycine Transport Platelet Dense Granule Lumen L-amino Acid Transmembrane Transporter Activity Alanine Transport Negative Regulation Of Meiotic Cell Cycle Female Meiotic Nuclear Division Neutral L-amino Acid Transmembrane Transporter Activity Synaptonemal Complex Assembly Scavenger Receptor Activity Oocyte Maturation Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition Synaptonemal Complex Organization Male Meiosis I Regulation Of Meiotic Nuclear Division Reciprocal Meiotic Recombination Microvillus Membrane Amino Acid Import Across Plasma Membrane Amino Acid Transmembrane Transporter Activity Peptide Antigen Binding Regulation Of Postsynaptic Neurotransmitter Receptor Internalization