CRIPT and TUBB

Number of citations of the paper that reports this interaction (PMID 9581762)
35

Data Source:
HPRD (in vivo)

		CRIPT	TUBB
Gene Name		cysteine-rich PDZ-binding protein	tubulin, beta class I
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Postsynaptic Density Cell Junction Dendrite Neuronal Cell Body Dendritic Spine Dendritic Shaft	Nucleus Nuclear Envelope Lumen Cytosol Cytoskeleton Microtubule Cytoplasmic Ribonucleoprotein Granule Cell Body Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Microtubule Binding PDZ Domain Binding Protein Complex Binding	GTPase Activity Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Protein Domain Specific Binding Ubiquitin Protein Ligase Binding Protein Complex Binding GTPase Activating Protein Binding MHC Class I Protein Binding
	Biological Process	Cytoplasmic Microtubule Organization Protein Localization To Microtubule Establishment Of Protein Localization Regulation Of Postsynaptic Density Protein 95 Clustering	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Movement Of Cell Or Subcellular Component Organelle Organization Microtubule-based Process Cellular Process Cytoskeleton-dependent Intracellular Transport Natural Killer Cell Mediated Cytotoxicity Spindle Assembly Protein Polymerization Cell Division
Pathways			Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs			Vinorelbine Vincristine Vinblastine Podofilox Colchicine Epothilone D Epothilone B
Diseases
GWAS		Height ( 20966902)
Protein-Protein Interactions		7 interactors: DLG1 DLG2 DLG3 DLG4 INADL TUBB UBQLN4	61 interactors: ALDOA APP ARL8B ATXN3 B4GALT1 BMPR2 BRCA1 CCT2 CDKN2A CLIP1 CMTM5 CNN1 CRIPT DISC1 DPYSL2 DYNLL1 ESR1 GDAP1 GNB2L1 GRM1 HDAC6 HGS HTRA2 HTT MAGEA2B MAL2 MAP1A MAP3K10 MAP4 MAP6 MAPRE1 MAPT MARK4 MRGBP MX1 NCALD NCAM1 NPHP1 PARK2 PFDN4 PLK1 RAB8B RASSF1 SDC3 SIRT2 SPP1 STAU1 SYT9 TAOK2 TBCD TGM2 TINF2 TTBK1 TTK TUBA1A VAV1 YWHAB YWHAG YWHAQ YWHAZ ZAP70
Entrez ID		9419	203068
HPRD ID		05208	01852
Ensembl ID		ENSG00000119878	ENSG00000196230
Uniprot IDs		Q9P021	B4DMJ5 P07437 Q5ST81 Q5SU16
PDB IDs			3QNZ 3QO0
Enriched GO Terms of Interacting Partners?		Receptor Localization To Synapse Protein Localization To Synapse Receptor Clustering Nucleotide Phosphorylation Establishment Or Maintenance Of Apical/basal Cell Polarity Protein Localization To Membrane Nucleotide Metabolic Process Synaptic Transmission Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Cell Polarity Nucleobase-containing Small Molecule Metabolic Process Cortical Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Membrane Organization Cell-cell Signaling Tight Junction Assembly Organophosphate Metabolic Process Negative Regulation Of Phosphatase Activity Axon Guidance Negative Regulation Of Dephosphorylation Cellular Localization Apical Junction Assembly Cellular Protein Localization Axonogenesis Regulation Of Phosphatase Activity Axon Development Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Neuron Differentiation Cell-cell Junction Assembly Chemotaxis Regulation Of Dephosphorylation Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Phosphorylation Cellular Component Assembly Protein Localization Neuron Projection Development T Cell Cytokine Production Cell Projection Morphogenesis Cell Junction Assembly Cell Part Morphogenesis Cell-cell Junction Organization Hard Palate Development Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Maintenance Of Apical/basal Cell Polarity Neuron Development Nervous System Development Negative Regulation Of Receptor Internalization Leukocyte Mediated Immunity	Regulation Of Cellular Component Organization Organelle Organization Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cytoskeleton Organization Microtubule Cytoskeleton Organization Positive Regulation Of Signal Transduction Cellular Localization Microtubule-based Process Regulation Of Organelle Organization Positive Regulation Of Apoptotic Process Programmed Cell Death Positive Regulation Of Organelle Organization Regulation Of Cell Death Cell Death Death Positive Regulation Of Cellular Protein Metabolic Process Apoptotic Process Cellular Response To Stimulus Regulation Of Cellular Process Cell Communication Cellular Protein Localization Regulation Of Cellular Localization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrion Organization Positive Regulation Of Protein Metabolic Process Regulation Of Signaling Signaling Regulation Of Apoptotic Process Positive Regulation Of Mitochondrion Organization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Intracellular Signal Transduction Response To Stimulus Regulation Of Signal Transduction Cell Cycle Signal Transduction Cell Cycle Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Cellular Protein Metabolic Process Mitotic Cell Cycle Process Regulation Of Microtubule-based Process Negative Regulation Of Protein Metabolic Process Mitotic Cell Cycle Nervous System Development Regulation Of Protein Localization
Tagcloud ?			3p ahi1 annotation clustering datasets demyelinating differential dqb1 dra eqtl eqtls grail highlighted hla loci ms ndfip1 publically relevance rs1062158 rs11154801 rs2647046 rs3095329 rs7194 rs9469220 snps tf trait utilizing
Tagcloud (Difference) ?			3p ahi1 annotation clustering datasets demyelinating differential dqb1 dra eqtl eqtls grail highlighted hla loci ms ndfip1 publically relevance rs1062158 rs11154801 rs2647046 rs3095329 rs7194 rs9469220 snps tf trait utilizing
Tagcloud (Intersection) ?