ARHGAP29 and RAP2A

Number of citations of the paper that reports this interaction (PMID 15752761)
7

Data Source:
HPRD (two hybrid, in vitro)

		ARHGAP29	RAP2A
Gene Name		Rho GTPase activating protein 29	RAP2A, member of RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Cytosol Plasma Membrane Midbody Recycling Endosome Recycling Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Rho GTPase Activator Activity PDZ Domain Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Positive Regulation Of Rho GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Positive Regulation Of Protein Phosphorylation Microvillus Assembly Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Positive Regulation Of Protein Autophosphorylation Rap Protein Signal Transduction Cellular Protein Localization Cellular Response To Drug Establishment Of Protein Localization Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of JNK Cascade Regulation Of Dendrite Morphogenesis Protein Localization To Plasma Membrane
Pathways		Rho GTPase cycle Signaling by Rho GTPases
Drugs			Guanosine-5\'-Triphosphate Guanosine-5\'-Diphosphate
Diseases
GWAS		D-dimer levels ( 21502573)
Protein-Protein Interactions		7 interactors: AKT1 CDC42 KDM1A MAGEA11 PTPN13 RAP2A RHOD	32 interactors: ACVR1 ARHGAP29 BMPR1B EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D MAP4K4 MLLT4 NEDD4 PLG RAF1 RALA RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK
Entrez ID		9411	5911
HPRD ID		06674	01547
Ensembl ID
Uniprot IDs		Q52LW3	P10114
PDB IDs			1KAO 2RAP 3RAP
Enriched GO Terms of Interacting Partners?		Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Regulation Of Signaling Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade Regulation Of Cellular Component Organization Regulation Of Organelle Organization Cell Projection Assembly Muscle Cell Differentiation Positive Regulation Of Cell Adhesion Cell Projection Organization Blood Coagulation Hemostasis Endomembrane System Organization Actin Filament Bundle Assembly Cellular Protein Localization T Cell Costimulation Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cell Projection Organization Gland Development Muscle Structure Development Adherens Junction Organization Organelle Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Glycogen Cell Differentiation Involved In Embryonic Placenta Development Regulation Of Primitive Erythrocyte Differentiation Regulation Of Cell Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Body Fluid Levels Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cell Migration Wound Healing Actin Cytoskeleton Organization Regulation Of MAPK Cascade Small GTPase Mediated Signal Transduction Regulation Of Cell Adhesion Regulation Of Cell Motility Myeloid Leukocyte Differentiation Actin Filament-based Process Regulation Of Locomotion Regulation Of Cellular Component Movement Response To Wounding Positive Regulation Of Hair Follicle Cell Proliferation Intracellular Signal Transduction Positive Regulation Of Protein Phosphorylation Regulation Of Protein Binding Protein Localization Regulation Of Cellular Protein Metabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway	Intracellular Signal Transduction Response To Stimulus Regulation Of Signaling Regulation Of Catalytic Activity Cell Communication Signal Transduction Cellular Response To Stimulus Positive Regulation Of Metabolic Process Positive Regulation Of Rap GTPase Activity Signaling Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Rap GTPase Activity Positive Regulation Of Catalytic Activity Regulation Of Rap Protein Signal Transduction Signal Transduction By Phosphorylation Regulation Of Metabolic Process Small GTPase Mediated Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Ras Protein Signal Transduction Regulation Of GTPase Activity Wound Healing Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Ras Protein Signal Transduction Regulation Of Dendrite Morphogenesis Response To Wounding Regulation Of Cell Projection Organization Positive Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Platelet Activation Regulation Of Ras GTPase Activity Cellular Response To Growth Factor Stimulus Response To Organic Substance Regulation Of Cellular Process Response To Growth Factor Regulation Of Dendrite Development Cardiovascular System Development Cell Surface Receptor Signaling Pathway Positive Regulation Of Ras GTPase Activity Regulation Of Cell Differentiation Negative Regulation Of Cell Proliferation Cell Activation Regulation Of Cellular Localization Cell Differentiation Blood Vessel Development Response To Stress Vasculature Development Regulation Of Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Activation Of MAPKK Activity
Tagcloud ?			cleave competitors degrades diaminopimelic effectors endopeptidase endopeptidases exploiting extrude heteromeric marcescens meso muropeptides neutralization neutralize orthologues pentapeptides promiscuity rap1a raps serratia ssp1 ssp2 steric tetrapenta tetrapeptides tetratetra tetratetrapeptides tripeptides
Tagcloud (Difference) ?			cleave competitors degrades diaminopimelic effectors endopeptidase endopeptidases exploiting extrude heteromeric marcescens meso muropeptides neutralization neutralize orthologues pentapeptides promiscuity rap1a raps serratia ssp1 ssp2 steric tetrapenta tetrapeptides tetratetra tetratetrapeptides tripeptides
Tagcloud (Intersection) ?