ARHGAP29

Description		Rho GTPase activating protein 29
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding PDZ Domain Binding Metal Ion Binding
	Biological Process	Signal Transduction Rho Protein Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) D-dimer levels ( 21502573) Plateletcrit ( 32888494) Systolic blood pressure ( 30224653)
Interacting Genes		7 interacting genes: HRAS KDM1A MAGEA11 PTPN13 RAP2A RHOA TRIM54
Entrez ID		9411
HPRD ID		06674
Ensembl ID		ENSG00000137962
Uniprot IDs		A0A2X0U4J5 Q52LW3
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein Activity Regulation Of Cellular Component Organization Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Cellular Response To Gamma Radiation Regulation Of Cell Junction Assembly Small GTPase-mediated Signal Transduction Regulation Of Synapse Organization GTPase Activity Response To Gamma Radiation Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Mitotic Cleavage Furrow Formation GTP Binding Regulation Of Intracellular Signal Transduction GDP Binding Cellular Response To Ionizing Radiation Positive Regulation Of Cell Projection Organization Regulation Of Cell Size Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Neuron Projection Development Positive Regulation Of Cellular Component Organization Positive Regulation Of Cellular Component Biogenesis Neuron Apoptotic Process Aortic Valve Formation Positive Regulation Of Vascular Associated Smooth Muscle Contraction Endothelial Tube Lumen Extension Regulation Of Neural Precursor Cell Proliferation Skeletal Muscle Satellite Cell Migration GTPase Complex Negative Regulation Of Excitatory Synapse Assembly Response To Toxic Substance Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Regulation Of Cytoskeleton Organization Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Cell Migration Beta Selection Positive Regulation Of Cell Motility Phospholipase C Activator Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Locomotion Response To Ionizing Radiation Regulation Of JNK Cascade Regulation Of Protein Modification Process Bone Trabecula Morphogenesis Protein Demethylase Activity Negative Regulation Of Metabolic Process Apolipoprotein A-I-mediated Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Regulation Of Microtubule Cytoskeleton Organization
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