ARHGAP29 and MAGEA11

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ARHGAP29	MAGEA11
Gene Name		Rho GTPase activating protein 29	melanoma antigen family A, 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Rho GTPase Activator Activity PDZ Domain Binding Metal Ion Binding	Protein Binding
	Biological Process	Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Positive Regulation Of Rho GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS		D-dimer levels ( 21502573)
Protein-Protein Interactions		7 interactors: AKT1 CDC42 KDM1A MAGEA11 PTPN13 RAP2A RHOD	86 interactors: ACMSD ACTN1 AKR1C3 ALDH5A1 AR ARHGAP29 BCL2L11 BEX2 BIRC2 C18orf54 CCDC14 CCDC146 CCDC185 CDC20B CDKN2B CEP76 CLUAP1 COX7A2L CSNK2A1 DIEXF DNAJC10 DOCK10 ENOX2 EWSR1 FAM156A GNPDA1 HOXB5 IL11 IL6ST ILF3 JADE3 KIAA0408 LNX1 MAPK3 MCRS1 MED28 MGME1 MLF1 MTA1 MXD3 MYOZ1 NCOA2 NDEL1 NDUFAF1 NDUFB9 NIF3L1 NOL4 NOS3 NSUN4 OTUB2 PCBD2 PDE4B PHYH PIN4 PNKD PNKP POLR1D PRDX3 PRKRIP1 PSMF1 RADIL RBM23 SH2D4A SNX20 SNX7 STAR TCEA2 TCEANC TCF25 TEX37 THEM5 TMEM123 TPM3 TRIM27 TRIM51 TRMT1 TXN2 UBE2D4 USP20 VTA1 WDYHV1 WTAP ZBTB16 ZCCHC12 ZNF655 ZSWIM2
Entrez ID		9411	4110
HPRD ID		06674	02281
Ensembl ID			ENSG00000185247
Uniprot IDs		Q52LW3	G5E962 P43364
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Regulation Of Signaling Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade Regulation Of Cellular Component Organization Regulation Of Organelle Organization Cell Projection Assembly Muscle Cell Differentiation Positive Regulation Of Cell Adhesion Cell Projection Organization Blood Coagulation Hemostasis Endomembrane System Organization Actin Filament Bundle Assembly Cellular Protein Localization T Cell Costimulation Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cell Projection Organization Gland Development Muscle Structure Development Adherens Junction Organization Organelle Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Glycogen Cell Differentiation Involved In Embryonic Placenta Development Regulation Of Primitive Erythrocyte Differentiation Regulation Of Cell Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Body Fluid Levels Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cell Migration Wound Healing Actin Cytoskeleton Organization Regulation Of MAPK Cascade Small GTPase Mediated Signal Transduction Regulation Of Cell Adhesion Regulation Of Cell Motility Myeloid Leukocyte Differentiation Actin Filament-based Process Regulation Of Locomotion Regulation Of Cellular Component Movement Response To Wounding Positive Regulation Of Hair Follicle Cell Proliferation Intracellular Signal Transduction Positive Regulation Of Protein Phosphorylation Regulation Of Protein Binding Protein Localization Regulation Of Cellular Protein Metabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway	Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Cellular Process Positive Regulation Of Metabolic Process Gene Expression Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Catabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Apoptotic Process Metabolic Process Protein Polyubiquitination Negative Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Testosterone Biosynthetic Process Regulation Of Cell Death Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Protein Metabolic Process Rhythmic Process Cell Death Response To Lipopolysaccharide Death Negative Regulation Of Protein Metabolic Process Respiratory Electron Transport Chain Response To Molecule Of Bacterial Origin Regulation Of Cell Cycle Electron Transport Chain Oxidation-reduction Process Negative Regulation Of Catalytic Activity RNA Methylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Apoptotic Process Reproductive Structure Development Positive Regulation Of Gene Expression Reproductive System Development Negative Regulation Of Mitotic Cell Cycle Phase Transition Programmed Cell Death
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