SFXN1 and CIDEB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SFXN1	CIDEB
Description		sideroflexin 1	cell death inducing DFFA like effector b
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Cytosol Membrane COPII Vesicle Coat COPI-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Monoatomic Ion Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity Transmembrane Transporter Activity	Protein Binding Identical Protein Binding Molecular Adaptor Activity Phosphatidic Acid Binding Lipid Transfer Activity
	Biological Process	One-carbon Metabolic Process Monoatomic Ion Transport Iron Ion Transport Amino Acid Transport L-alanine Transport L-serine Transport Erythrocyte Differentiation Monoatomic Ion Transmembrane Transport Transmembrane Transport Serine Import Into Mitochondrion	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Lipid Storage Response To Nutrient Levels Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Apoptotic Process COPII-coated Vesicle Cargo Loading Regulation Of Triglyceride Metabolic Process Execution Phase Of Apoptosis Intermembrane Lipid Transfer Lipid Droplet Fusion
Pathways
Drugs
Diseases
GWAS		Height ( 28552196) Metabolite levels ( 23823483) Mosquito bite size ( 28199695) Night sleep phenotypes ( 27126917)	Anorectal malformation ( 31136621) Height ( 28552196) Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		14 interacting genes: AQP6 CIDEB FCER1G HSD17B13 MMD PGRMC2 SCN3B SLC10A1 SLC10A6 SLC16A7 STOM TLCD4 TMEM14B TMX2	68 interacting genes: ABHD16A AFG1L APOC1 ARL8B ATP5ME ATP5MJ BCL2L2 CAND2 CIDEA CLCN1 CMPK1 COL10A1 COL8A1 COX7C DFFA DFFB DHRSX DNAJA3 FAM218A FAM47E-STBD1 FKBP8 FOXD4L3 FUNDC2 GCSH GNB3 GPAM H4C7 HAPLN2 HCCS HIGD1C IRX2-DT MEST MICOS10 MPC2 MRPL36 MRPL57 MTERF4 NAALAD2 NDRG4 NFU1 NME4 PBX3 PDHX PGLYRP3 PISD PPIF RAMP2 RHBDD2 ROMO1 RTP5 SAA2 SAA4 SAR1B SCO1 SCO2 SDHAF1 SFXN1 SMARCC1 SPG21 TAOK2 TBX2 TEX44 THBD TIMM17B TMEM14B TPRG1 TSR1 UFSP1
Entrez ID		94081	27141
HPRD ID		18044	11981
Ensembl ID		ENSG00000164466	ENSG00000136305
Uniprot IDs		Q9H9B4	Q9UHD4
PDB IDs			1D4B
Enriched GO Terms of Interacting Partners?		Organic Hydroxy Compound Transport Bile Acid:sodium Symporter Activity Membrane Symporter Activity Bile Acid And Bile Salt Transport Monocarboxylic Acid Transport Sodium Ion Transport Nitrate Transmembrane Transporter Activity Monoatomic Ion Transport Endoplasmic Reticulum IgE Receptor Activity Pyruvate Secondary Active Transmembrane Transporter Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Transmembrane Transport Tertiary Granule Membrane Positive Regulation Of Type I Hypersensitivity Fc-epsilon Receptor I Complex Carboxylic Acid Transport Organic Acid Transport Metal Ion Transport Secondary Active Monocarboxylate Transmembrane Transporter Activity Identical Protein Binding Negative Regulation Of Mast Cell Apoptotic Process Serotonin Secretion By Platelet Fc-gamma Receptor III Complex Positive Regulation Of Type III Hypersensitivity Monoatomic Cation Transport Lipid Transport Organic Anion Transport Lipid Droplet Steroid Dehydrogenase Activity Mast Cell Apoptotic Process Serotonin Secretion Positive Regulation Of Type IIa Hypersensitivity Pyruvate Transmembrane Transporter Activity Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Positive Regulation Of Mast Cell Cytokine Production IgE Binding Regulation Of Mast Cell Apoptotic Process Plasma Membrane Lactate Transport Pyruvate Transmembrane Transport Lipid Droplet Fusion Lactate Transmembrane Transporter Activity Pyruvate Transport SA Node Cell Action Potential	Mitochondrion Mitochondrial Inner Membrane Regulation Of Apoptotic DNA Fragmentation Negative Regulation Of Apoptotic DNA Fragmentation High-density Lipoprotein Particle Protein Binding Mitochondrion Organization Mitochondrial Membrane Copper Chaperone Activity Disordered Domain Specific Binding T Cell Apoptotic Process Mitochondrial Matrix Organophosphate Biosynthetic Process Cytochrome Complex Assembly Pyruvate Decarboxylation To Acetyl-CoA Activation-induced Cell Death Of T Cells Mitochondrial Respiratory Chain Complex Assembly Lymphocyte Apoptotic Process Import Into The Mitochondrion Negative Regulation Of Execution Phase Of Apoptosis Protein Localization To Mitochondrion
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