SFXN1 and SLC16A7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SFXN1	SLC16A7
Description		sideroflexin 1	solute carrier family 16 member 7
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Basolateral Plasma Membrane Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Parallel Fiber To Purkinje Cell Synapse Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding Monoatomic Ion Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity Transmembrane Transporter Activity	Pyruvate Secondary Active Transmembrane Transporter Activity Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Lactate Transmembrane Transporter Activity Symporter Activity Secondary Active Monocarboxylate Transmembrane Transporter Activity Transmembrane Transporter Activity Identical Protein Binding Pyruvate Transmembrane Transporter Activity
	Biological Process	One-carbon Metabolic Process Monoatomic Ion Transport Iron Ion Transport Amino Acid Transport L-alanine Transport L-serine Transport Erythrocyte Differentiation Monoatomic Ion Transmembrane Transport Transmembrane Transport Serine Import Into Mitochondrion	Monocarboxylic Acid Transport Lactate Transmembrane Transport Plasma Membrane Lactate Transport Transmembrane Transport Transport Across Blood-brain Barrier Pyruvate Transmembrane Transport
Pathways			Proton-coupled monocarboxylate transport
Drugs			Pyruvic acid
Diseases
GWAS		Height ( 28552196) Metabolite levels ( 23823483) Mosquito bite size ( 28199695) Night sleep phenotypes ( 27126917)	Adventurousness ( 30643258) Calcium levels ( 25972035) General risk tolerance (MTAG) ( 30643258) Hematocrit ( 29403010) Kawasaki disease ( 33692975) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901) Takayasu arteritis ( 25604533)
Interacting Genes		14 interacting genes: AQP6 CIDEB FCER1G HSD17B13 MMD PGRMC2 SCN3B SLC10A1 SLC10A6 SLC16A7 STOM TLCD4 TMEM14B TMX2	15 interacting genes: ACSL5 CDIPT COMT CPEB1 FXYD6 GPR25 HMOX1 IFITM3 LEMD1 SFXN1 SMAGP SNTA1 TIMM23 VAPA VTI1B
Entrez ID		94081	9194
HPRD ID		18044	06791
Ensembl ID		ENSG00000164466	ENSG00000118596
Uniprot IDs		Q9H9B4	O60669
PDB IDs			7BP3
Enriched GO Terms of Interacting Partners?		Organic Hydroxy Compound Transport Bile Acid:sodium Symporter Activity Membrane Symporter Activity Bile Acid And Bile Salt Transport Monocarboxylic Acid Transport Sodium Ion Transport Nitrate Transmembrane Transporter Activity Monoatomic Ion Transport Endoplasmic Reticulum IgE Receptor Activity Pyruvate Secondary Active Transmembrane Transporter Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Transmembrane Transport Tertiary Granule Membrane Positive Regulation Of Type I Hypersensitivity Fc-epsilon Receptor I Complex Carboxylic Acid Transport Organic Acid Transport Metal Ion Transport Secondary Active Monocarboxylate Transmembrane Transporter Activity Identical Protein Binding Negative Regulation Of Mast Cell Apoptotic Process Serotonin Secretion By Platelet Fc-gamma Receptor III Complex Positive Regulation Of Type III Hypersensitivity Monoatomic Cation Transport Lipid Transport Organic Anion Transport Lipid Droplet Steroid Dehydrogenase Activity Mast Cell Apoptotic Process Serotonin Secretion Positive Regulation Of Type IIa Hypersensitivity Pyruvate Transmembrane Transporter Activity Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Positive Regulation Of Mast Cell Cytokine Production IgE Binding Regulation Of Mast Cell Apoptotic Process Plasma Membrane Lactate Transport Pyruvate Transmembrane Transport Lipid Droplet Fusion Lactate Transmembrane Transporter Activity Pyruvate Transport SA Node Cell Action Potential	Membrane
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