ZRANB2 and SRSF2

Number of citations of the paper that reports this interaction (PubMedID 11448987)
58

Data Source:
HPRD (in vivo)

		ZRANB2	SRSF2
Description		zinc finger RANBP2-type containing 2	serine and arginine rich splicing factor 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Cytosol PML Body Nuclear Speck
	Molecular Function	Lipopolysaccharide Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Nucleic Acid Binding Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding
	Biological Process	RNA Processing MRNA Processing RNA Splicing	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Negative Regulation Of DNA-templated Transcription
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Dental caries (decayed, missing and filled teeth) ( 31533690) Verbal declarative memory ( 25648963)
Interacting Genes		17 interacting genes: AKAP17A CEBPA CSNK2A1 EP300 KIF20A LRRK2 OGT SMN1 SNRNP70 SREK1 SRPK1 SRPK2 SRSF2 TRA2B U2AF1 UBC YY1	36 interacting genes: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIRSR CSNK2A1 DMRTB1 FUS GEMIN2 GOLGA2 KAT5 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC PRPF6 SCAF11 SNRNP70 SREK1 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 USP40 YTHDC1 ZRANB2 ZRSR2
Entrez ID		9406	6427
HPRD ID		09185	02888
Ensembl ID		ENSG00000132485	ENSG00000161547
Uniprot IDs		O95218	Q01130 Q53FN0
PDB IDs		1N0Z 2K1P 3G9Y	2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Metabolic Process MRNA Processing RNA Metabolic Process Nucleoplasm Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Macromolecule Metabolic Process RNA Binding Regulation Of RNA Splicing RNA Processing Regulation Of MRNA Splicing, Via Spliceosome Nuclear Speck Regulation Of MRNA Processing Spliceosomal Complex Nucleus Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Gene Expression Regulation Of MRNA Metabolic Process Nucleic Acid Binding Spliceosomal Complex Assembly Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Regulation Of Proteasomal Protein Catabolic Process RNA Splicing, Via Transesterification Reactions STAT Family Protein Binding Regulation Of RNA Metabolic Process Chromatin DNA Binding Negative Regulation Of Autophagy Regulation Of Nucleobase-containing Compound Metabolic Process Sin3-type Complex Negative Regulation Of Protein Catabolic Process Regulation Of Gene Expression Histone Acetyltransferase Complex Nuclear Matrix Protein Kinase A Binding Regulation Of Macromolecule Biosynthetic Process PcG Protein Complex Protein Serine Kinase Activity Negative Regulation Of Proteolysis Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Macrophage Activation Regulation Of Primary Metabolic Process Positive Regulation Of Viral Genome Replication Regulation Of Autophagy Regulation Of Proteolysis Protein Serine/threonine Kinase Activity Hemopoiesis Positive Regulation Of Proteolysis	RNA Splicing MRNA Processing MRNA Metabolic Process Nuclear Speck RNA Processing Nucleic Acid Metabolic Process RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Nucleoplasm RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nucleus Spliceosomal Complex Nucleic Acid Binding Regulation Of MRNA Processing RNA Binding Macromolecule Metabolic Process Cyclin-dependent Protein Kinase Holoenzyme Complex Spliceosomal Complex Assembly Regulation Of MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Aggrephagy Regulation Of RNA Metabolic Process Protein-RNA Complex Assembly Pre-mRNA 3'-splice Site Binding U2AF Complex Negative Regulation Of Autophagy Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Regulation Of DNA Repair Regulation Of Autophagy Negative Regulation Of Catabolic Process Negative Regulation Of DNA Recombination MRNA Binding Regulation Of DNA Recombination Double-strand Break Repair Via Classical Nonhomologous End Joining Regulation Of Double-strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Membraneless Organelle Assembly Cellular Response To Glucose Stimulus Aggrephagy Protein Targeting To Vacuole Involved In Autophagy Sequence-specific MRNA Binding Regulation Of Hematopoietic Stem Cell Differentiation Cellular Response To Carbohydrate Stimulus
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