ZRANB2 and SRSF2

Number of citations of the paper that reports this interaction (PMID 11448987)
13

Data Source:
HPRD (in vivo)

		ZRANB2	SRSF2
Gene Name		zinc finger, RAN-binding domain containing 2	serine/arginine-rich splicing factor 2
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm PML Body Nuclear Speck Extracellular Vesicular Exosome
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity RNA Binding Protein Binding Zinc Ion Binding Poly(A) RNA Binding	Nucleotide Binding Transcription Corepressor Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated MRNA Processing RNA Splicing	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Negative Regulation Of Nucleic Acid-templated Transcription
Pathways			mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: AKAP17A CSNK2A1 EP300 KIF20A SMN1 SNRNP70 SREK1 SRPK1 SRPK2 SRSF2 TRA2B U2AF1 YY1	33 interactors: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIR1 CSNK2A1 FUS GEMIN2 GOLGA2 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC SCAF11 SNRNP70 SREK1 SRSF1 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 YTHDC1 ZRANB2 ZRSR2
Entrez ID		9406	6427
HPRD ID		09185	02888
Ensembl ID		ENSG00000132485	ENSG00000161547
Uniprot IDs		O95218	Q01130 Q53FN0
PDB IDs		1N0Z 2K1P 3G9Y	2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Nitrogen Compound Metabolic Process Positive Regulation Of Viral Process Positive Regulation Of Viral Genome Replication RNA Localization Regulation Of Viral Process Regulation Of RNA Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Termination Of RNA Polymerase II Transcription Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Viral Genome Replication Cellular Metabolic Process Spliceosomal Complex Assembly Histone H2B Acetylation Nuclear Speck Organization MRNA Export From Nucleus Regulation Of Viral Genome Replication DNA-templated Transcription, Termination RNA Export From Nucleus Negative Regulation Of Viral Process Metabolic Process MRNA 3'-end Processing Positive Regulation Of Gene Expression Response To Prostaglandin F Regulation Of Gene Expression RNA 3'-end Processing N-terminal Peptidyl-lysine Acetylation Nuclear Export MRNA Transport Nucleus Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response RNA Transport Regulation Of Tubulin Deacetylation Ribonucleoprotein Complex Assembly Sperm Chromatin Condensation	RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Termination Of RNA Polymerase II Transcription Nitrogen Compound Metabolic Process Nuclear Export Spliceosomal Complex Assembly MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus Nucleocytoplasmic Transport Nuclear Transport MRNA 3'-end Processing Regulation Of MRNA Processing RNA 3'-end Processing MRNA Transport RNA Transport Cellular Macromolecular Complex Assembly RNA Localization Regulation Of MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex Assembly Cell Cycle Regulation Of RNA Splicing Regulation Of Cell Cycle Cytoplasmic Transport Cellular Metabolic Process Mitotic Cell Cycle Cell Cycle Process Ribonucleoprotein Complex Biogenesis Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Intracellular Transport RNA Biosynthetic Process Mitotic Cell Cycle Process Negative Regulation Of Cell Cycle Cellular Component Assembly Positive Regulation Of MRNA Splicing, Via Spliceosome DNA Strand Elongation Involved In DNA Replication Cellular Localization DNA Strand Elongation Regulation Of Protein Export From Nucleus
Tagcloud ?		as2 chip clone cne coding cur curcumin curve cytometry differentially enhancement fcm fitted flj36000 g2 graph gucy2gp h2bfxp incrna linc00623 loc100506835 micro nasopharyngeal prism radiosensitivity radiosensitizing sensitization verified worked	asxl1 biologic clonal cmml created cytopenias dependence discern dysplasia entity extramedullary extrapolation focuses granulocyte hematologic identifies landscape macrophage makes malignancy monocytosis myelomonocytic ontology propensity scientific speculative supporting tools troublesome
Tagcloud (Difference) ?		as2 chip clone cne coding cur curcumin curve cytometry differentially enhancement fcm fitted flj36000 g2 graph gucy2gp h2bfxp incrna linc00623 loc100506835 micro nasopharyngeal prism radiosensitivity radiosensitizing sensitization verified worked	asxl1 biologic clonal cmml created cytopenias dependence discern dysplasia entity extramedullary extrapolation focuses granulocyte hematologic identifies landscape macrophage makes malignancy monocytosis myelomonocytic ontology propensity scientific speculative supporting tools troublesome
Tagcloud (Intersection) ?