ZRANB2 and U2AF1

Number of citations of the paper that reports this interaction (PubMedID 11448987)
58

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		ZRANB2	U2AF1
Description		zinc finger RANBP2-type containing 2	U2 small nuclear RNA auxiliary factor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome U2AF Complex
	Molecular Function	Lipopolysaccharide Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding RS Domain Binding
	Biological Process	RNA Processing MRNA Processing RNA Splicing	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Dental caries (decayed, missing and filled teeth) ( 31533690) Verbal declarative memory ( 25648963)	Blood and toenail selenium levels ( 25343990)
Interacting Genes		17 interacting genes: AKAP17A CEBPA CSNK2A1 EP300 KIF20A LRRK2 OGT SMN1 SNRNP70 SREK1 SRPK1 SRPK2 SRSF2 TRA2B U2AF1 UBC YY1	58 interacting genes: ALG13 AP1B1 AP2B1 CARNMT1 CHERP CIRSR CLK2 CPEB2 DHX38 EFHC2 EPB41 FILNC1 FRA10AC1 HINFP HMGB2 HNRNPK HNRNPM IL7R JMJD6 KRT1 KRT75 MAP1B MEOX2 MFAP1 MLH1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A PTEN RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRNP35 SNRPD1 SRPK1 SRPK2 SRRM4 SRSF1 SRSF2 SRSF3 SUV39H1 TOE1 TRA2B U2AF2 VEGFA VPS26C WEE2-AS1 ZCCHC10 ZNF417 ZRANB2 ZRSR2
Entrez ID		9406	7307
HPRD ID		09185	01871
Ensembl ID		ENSG00000132485	ENSG00000160201
Uniprot IDs		O95218	Q01081 Q7Z780
PDB IDs		1N0Z 2K1P 3G9Y	1JMT
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Metabolic Process MRNA Processing RNA Metabolic Process Nucleoplasm Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Macromolecule Metabolic Process RNA Binding Regulation Of RNA Splicing RNA Processing Regulation Of MRNA Splicing, Via Spliceosome Nuclear Speck Regulation Of MRNA Processing Spliceosomal Complex Nucleus Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Gene Expression Regulation Of MRNA Metabolic Process Nucleic Acid Binding Spliceosomal Complex Assembly Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Regulation Of Proteasomal Protein Catabolic Process RNA Splicing, Via Transesterification Reactions STAT Family Protein Binding Regulation Of RNA Metabolic Process Chromatin DNA Binding Negative Regulation Of Autophagy Regulation Of Nucleobase-containing Compound Metabolic Process Sin3-type Complex Negative Regulation Of Protein Catabolic Process Regulation Of Gene Expression Histone Acetyltransferase Complex Nuclear Matrix Protein Kinase A Binding Regulation Of Macromolecule Biosynthetic Process PcG Protein Complex Protein Serine Kinase Activity Negative Regulation Of Proteolysis Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Macrophage Activation Regulation Of Primary Metabolic Process Positive Regulation Of Viral Genome Replication Regulation Of Autophagy Regulation Of Proteolysis Protein Serine/threonine Kinase Activity Hemopoiesis Positive Regulation Of Proteolysis	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Spliceosomal Complex Regulation Of MRNA Splicing, Via Spliceosome RNA Binding Nucleic Acid Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Splicing Nuclear Speck Nucleic Acid Binding Nucleobase-containing Compound Metabolic Process Spliceosomal Complex Assembly Regulation Of MRNA Metabolic Process Catalytic Step 2 Spliceosome Nucleus Nucleoplasm Protein-RNA Complex Assembly Macromolecule Metabolic Process MRNA Binding U2-type Precatalytic Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Metabolic Process U12-type Spliceosomal Complex Negative Regulation Of RNA Splicing U2-type Spliceosomal Complex Positive Regulation Of RNA Splicing Precatalytic Spliceosome U1 SnRNP Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ribonucleoprotein Complex Negative Regulation Of RNA Metabolic Process Protein-containing Complex Assembly U2-type Prespliceosome Assembly Regulation Of Nucleobase-containing Compound Metabolic Process U2 SnRNP Commitment Complex Positive Regulation Of Viral Genome Replication Pre-mRNA 3'-splice Site Binding U2AF Complex MRNA Splice Site Recognition Regulation Of RNA Metabolic Process Protein-containing Complex Organization MRNA 5'-splice Site Recognition T Cell Differentiation In Thymus
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