TSNAXIP1 and UTP6

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		TSNAXIP1	UTP6
Description		translin associated factor X interacting protein 1	UTP6 small subunit processome component
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Chromosome Nucleolus Small-subunit Processome Pwp2p-containing Subcomplex Of 90S Preribosome
	Molecular Function	Protein Binding	Protein Binding SnoRNA Binding
	Biological Process	Spermatogenesis Cell Differentiation	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing RNA Processing Ribosomal Small Subunit Biogenesis
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		A body shape index ( 34021172) Empathy quotient ( 29527006) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	High chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183)
Interacting Genes		12 interacting genes: APP CDC7 FAM161B GRAP2 HSPB1 PRPF18 PRPF6 ROPN1 SNW1 SPG21 TSNAX UTP6	8 interacting genes: CCDC85B ESS2 KXD1 QKI RHOXF2 TFIP11 TRAK1 TSNAXIP1
Entrez ID		55815	55813
HPRD ID		09656	11020
Ensembl ID		ENSG00000102904	ENSG00000108651
Uniprot IDs		B4DXD0 E7ENJ7 Q2TAA8	Q9NYH9
PDB IDs			7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?		Collateral Sprouting Neuron Maturation Cell Maturation RNA Processing Spliceosomal Complex U5 SnRNP Developmental Maturation U4/U6 X U5 Tri-snRNP Complex Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Protein Kinase C Signaling U2-type Post-spliceosomal Complex Positive Regulation Of Interleukin-1 Beta Production Acetylcholine Receptor Activator Activity PTB Domain Binding Positive Regulation Of Interleukin-1 Production Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Axo-dendritic Transport Response To Growth Factor Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Nucleus Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Interleukin-1 Beta Production Protein Kinase C Inhibitor Activity A2A Adenosine Receptor Binding Generation Of Catalytic Spliceosome For Second Transesterification Step RNA Splicing Catalytic Step 2 Spliceosome Microtubule-based Movement Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Interleukin-1 Production Axon Midline Choice Point Recognition Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Developmental Cell Growth	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing Catalytic Step 2 Spliceosome Myofibroblast Contraction Internal N(7)-methylguanine-containing RNA Reader Activity Negative Regulation Of MiRNA Catabolic Process Organelle Transport Along Microtubule Spliceosomal Complex Disassembly Developmental Process U2-type Post-mRNA Release Spliceosomal Complex
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