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CPNE6 and MAPK11
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
0
Data Source:
BioGRID
(two hybrid)
CPNE6
MAPK11
Description
copine 6
mitogen-activated protein kinase 11
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Endosome
Plasma Membrane
Membrane
Clathrin-coated Vesicle
Axon
Dendrite
Cytoplasmic Vesicle
Cell Projection
Perikaryon
Clathrin-coated Endocytic Vesicle
Extracellular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
Phosphatidylserine Binding
Calcium Ion Binding
Protein Binding
Calcium-dependent Phospholipid Binding
Metal Ion Binding
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
MAP Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Protein Serine Kinase Activity
Biological Process
Cell Differentiation
Cellular Response To Calcium Ion
Postsynaptic Actin Cytoskeleton Organization
Positive Regulation Of Dendrite Extension
MAPK Cascade
Osteoblast Differentiation
Positive Regulation Of Gene Expression
Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of Interleukin-12 Production
Intracellular Signal Transduction
P38MAPK Cascade
Positive Regulation Of Erythrocyte Differentiation
Positive Regulation Of Muscle Cell Differentiation
Stress-activated MAPK Cascade
Protein Maturation
Cardiac Muscle Cell Proliferation
Regulation Of Cardiac Muscle Cell Proliferation
Negative Regulation Of Cardiac Muscle Cell Proliferation
Bone Development
Pyroptotic Inflammatory Response
Cellular Response To Interleukin-1
Cellular Response To UV-B
Cellular Senescence
Cellular Response To Virus
NLRP1 Inflammasome Complex Assembly
Pathways
Glycerophospholipid biosynthesis
NOD1/2 Signaling Pathway
p38MAPK events
p38MAPK events
ERK/MAPK targets
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Oxidative Stress Induced Senescence
VEGFA-VEGFR2 Pathway
activated TAK1 mediates p38 MAPK activation
Activation of the AP-1 family of transcription factors
KSRP (KHSRP) binds and destabilizes mRNA
Myogenesis
Myogenesis
RHO GTPases Activate NADPH Oxidases
Regulation of TP53 Activity through Phosphorylation
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A
Drugs
Minocycline
KC706
Regorafenib
Diseases
GWAS
Triglyceride levels (
32203549
)
Acne (severe) (
24927181
)
Adult body size (
32376654
)
Interacting Genes
14 interacting genes:
AGR2
AK5
ANXA7
CDKN1A
GRB7
LAMTOR3
MAPK11
MEOX2
NOTCH3
OS9
PIN1
SMN1
TK1
TTR
28 interacting genes:
APP
ATF2
BCL2
C9orf78
CCND1
CPNE6
DOT1L
DUSP10
DUSP16
EEF2K
ELK1
ELK4
ESR2
HDAC3
HTRA2
JUN
MAPKAPK5
MAPT
MBP
NOXA1
PML
POLR3D
PPM1D
RPS6KA5
SH2D1A
SOCS3
TAB1
ZNHIT1
Entrez ID
9362
5600
HPRD ID
05748
04208
Ensembl ID
ENSG00000100884
ENSG00000185386
Uniprot IDs
O95741
Q15759
PDB IDs
3GC8
3GC9
3GP0
8YGW
Enriched GO Terms of Interacting Partners
?
Cellular Response To UV-B
Intracellular Signal Transduction
Mitogen-activated Protein Kinase P38 Binding
Regulation Of Growth
Regulation Of Metabolic Process
Regulation Of Cell Cycle
Regulation Of Developmental Growth
Chromatin Binding
Response To Metal Ion
Negative Regulation Of Metabolic Process
Negative Regulation Of Cell Cycle
Regulation Of Gene Expression
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Multicellular Organismal Process
Regulation Of Macromolecule Biosynthetic Process
Cellular Response To Stress
Enzyme Binding
Regulation Of Neuron Apoptotic Process
Regulation Of Signal Transduction
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Developmental Process
Regulation Of Multicellular Organism Growth
Signal Transduction In Response To DNA Damage
Positive Regulation Of RNA Biosynthetic Process
Epigenetic Regulation Of Gene Expression
Regulation Of Intracellular Signal Transduction
Positive Regulation Of DNA-templated Transcription
Response To Stress
Mitogen-activated Protein Kinase Binding
Regulation Of Developmental Process
Chromatin Remodeling
Cellular Response To Anisomycin
Nucleus
Positive Regulation Of RNA Metabolic Process
Protein Serine/threonine Phosphatase Activity
Negative Regulation Of Macromolecule Biosynthetic Process
Cytosol
Microglial Cell Activation
Response To Anisomycin
Positive Regulation Of Metabolic Process
Regulation Of Signaling
Regulation Of Cell Communication
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Leukocyte Activation Involved In Inflammatory Response
Nucleoplasm
Negative Regulation Of RNA Biosynthetic Process
Main Axon
Liver Development
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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