CPNE6 and LAMTOR3

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		CPNE6	LAMTOR3
Description		copine 6	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Plasma Membrane Membrane Clathrin-coated Vesicle Axon Dendrite Cytoplasmic Vesicle Cell Projection Perikaryon Clathrin-coated Endocytic Vesicle Extracellular Exosome	Cytoplasm Lysosomal Membrane Endosome Late Endosome Plasma Membrane Focal Adhesion Endosome Membrane Membrane Late Endosome Membrane Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane Ragulator Complex FNIP-folliculin RagC/D GAP
	Molecular Function	Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Activator Activity Molecular Adaptor Activity
	Biological Process	Cell Differentiation Cellular Response To Calcium Ion Postsynaptic Actin Cytoskeleton Organization Positive Regulation Of Dendrite Extension	Intracellular Protein Localization Regulation Of TOR Signaling Positive Regulation Of TOR Signaling TORC1 Signaling Positive Regulation Of MAPK Cascade Cellular Response To Amino Acid Stimulus Protein Localization To Cell Junction Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of TORC1 Signaling
Pathways		Glycerophospholipid biosynthesis	Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes MAP2K and MAPK activation Neutrophil degranulation Regulation of PTEN gene transcription Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Triglyceride levels ( 32203549)	Mean reticulocyte volume ( 32888494)
Interacting Genes		14 interacting genes: AGR2 AK5 ANXA7 CDKN1A GRB7 LAMTOR3 MAPK11 MEOX2 NOTCH3 OS9 PIN1 SMN1 TK1 TTR	20 interacting genes: ADAMTS10 APOL6 BHMT CEBPZ CPNE6 IBTK LAMTOR2 MAP2K1 MAP2K2 MAPK1 MAPK3 MBD2 NIF3L1 PDE4DIP QARS1 SUFU TFE3 TGM7 UBR1 ZSCAN4
Entrez ID		9362	8649
HPRD ID		05748	04485
Ensembl ID		ENSG00000100884	ENSG00000109270
Uniprot IDs		O95741	Q9UHA4
PDB IDs			1SKO 2ZL1 3CPT 5X6U 5X6V 5Y39 5Y3A 5YK3 6B9X 6EHP 6EHR 6NZD 6U62 6ULG 6WJ2 6WJ3 7T3A 7T3B 7T3C 7UX2 7UXC 7UXH 8DHB
Enriched GO Terms of Interacting Partners?		Cellular Response To UV-B	Regulation Of Golgi Inheritance Regulation Of Golgi Organization Trachea Formation ERBB3 Signaling Pathway ERBB2-ERBB3 Signaling Pathway Regulation Of Stress-activated MAPK Cascade Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Early Endosome To Late Endosome Transport Schwann Cell Development Animal Organ Formation Face Development ERBB2 Signaling Pathway Lung Morphogenesis Thyroid Gland Development Insulin-like Growth Factor Receptor Signaling Pathway Bergmann Glial Cell Differentiation Thymus Development ERK1 And ERK2 Cascade Late Endosome Glial Cell Development ERBB Signaling Pathway Myelination Interleukin-34-mediated Signaling Pathway Axon Ensheathment Hematopoietic Or Lymphoid Organ Development Astrocyte Differentiation Regulation Of Intracellular Transport Caveolin-mediated Endocytosis Positive Regulation Of Macrophage Proliferation Epithelial Cell Proliferation Involved In Lung Morphogenesis Cardiac Neural Crest Cell Development Involved In Heart Development Outer Ear Morphogenesis Molecular Adaptor Activity Regulation Of MAPK Cascade MAP-kinase Scaffold Activity MAPK Cascade MAP Kinase Kinase Activity MAP Kinase Activity Pseudopodium Regulation Of DNA-templated Transcription Gland Development Regulation Of RNA Biosynthetic Process Positive Regulation Of Macrophage Chemotaxis Glial Cell Differentiation Positive Regulation Of Neuroinflammatory Response Regulation Of Cellular Localization Regulation Of Cellular Response To Stress Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Cytoplasm
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