ZNHIT3 and ZNF24

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		ZNHIT3	ZNF24
Description		zinc finger HIT-type containing 3	zinc finger protein 24
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Pre-snoRNP Complex	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding Nuclear Thyroid Hormone Receptor Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Box C/D SnoRNP Assembly Regulation Of DNA-templated Transcription	Regulation Of Transcription By RNA Polymerase II Myelination Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Multiple sclerosis ( 31604244) Red cell distribution width ( 27863252 28957414 32888494)
Interacting Genes		13 interacting genes: CSNK2A2 ESR2 FCMR HNF4A MBNL1 MEIS2 PBX3 PITX2 PPARG RXRA THRB XRCC3 ZNF24	47 interacting genes: APLP1 CEP126 COPS6 CRMP1 DDX6 DZIP3 EEF1A1 EEF1G ERG28 FAM161A FANCA HAP1 HMGB1 KAT5 LMO1 LMO2 LRIF1 MAP1LC3C MID2 NEK6 PPP1CC PRPF31 RBM48 SCAND1 SEC62 SETDB1 TCAF1 TP53 TRIM25 TRIM41 UBE2I UNC119 UTP14A YJU2B ZBTB16 ZGPAT ZKSCAN8 ZNF165 ZNF174 ZNF410 ZNF446 ZNF620 ZNHIT3 ZSCAN12 ZSCAN16 ZSCAN22 ZSCAN32
Entrez ID		9326	7572
HPRD ID		05139	01921
Ensembl ID		ENSG00000273611	ENSG00000172466
Uniprot IDs		Q15649	P17028
PDB IDs		2YQQ 5L85	1X6E 3LHR
Enriched GO Terms of Interacting Partners?		Sequence-specific DNA Binding Nuclear Receptor Activity RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Intracellular Receptor Signaling Pathway Retinoic Acid Receptor Signaling Pathway Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Nuclear Receptor-mediated Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Negative Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Hormone-mediated Signaling Pathway DNA Binding Domain Binding Nucleoplasm Positive Regulation Of Lipoprotein Transport MRNA Transcription By RNA Polymerase II Regulation Of Thyroid Hormone Receptor Signaling Pathway Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Activator Activity, RNA Polymerase II-specific LBD Domain Binding MRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Transcription Cis-regulatory Region Binding Peroxisome Proliferator Activated Receptor Signaling Pathway Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Sequence-specific Double-stranded DNA Binding Negative Regulation Of Macromolecule Biosynthetic Process Transcription By RNA Polymerase II Nucleus Negative Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Monocyte Differentiation Eye Development Nuclear Steroid Receptor Activity RNA Polymerase II Transcription Regulator Complex	Zinc Ion Binding Nucleus Regulation Of Macromolecule Metabolic Process Metal Ion Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Gene Expression Protein Binding Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Transcription Coactivator Activity DNA-binding Transcription Factor Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding
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