CYTH3 and TAMALIN

Number of citations of the paper that reports this interaction (PubMedID 10828067)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		CYTH3	TAMALIN
Description		cytohesin 3	trafficking regulator and scaffold protein tamalin
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GO Annotations	Cellular Component	Golgi Membrane Ruffle Nucleoplasm Cytoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Membrane Anchoring Junction	Cytoplasm Plasma Membrane Postsynaptic Density Membrane Synapse Postsynaptic Membrane Perinuclear Region Of Cytoplasm Glutamatergic Synapse
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Lipid Binding	PDZ Domain Binding Small GTPase Binding Identical Protein Binding
	Biological Process	Regulation Of ARF Protein Signal Transduction Positive Regulation Of Cell Adhesion Golgi Vesicle Transport Establishment Of Epithelial Cell Polarity	Signal Transduction Regulation Of Postsynaptic Neurotransmitter Receptor Internalization
Pathways		Intra-Golgi traffic
Drugs		Inositol 1,3,4,5-Tetrakisphosphate Inositol-(1,3,4,5,6)-Pentakisphosphate
Diseases
GWAS		Asthma ( 27611488) Body mass index ( 26426971) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Shigella-associated diarrhea ( 33649051)
Interacting Genes		10 interacting genes: ARFIP2 CALCOCO1 CNKSR1 CYTIP FRMD4B IFI35 ITSN1 PIK3CA SNCA TAMALIN	12 interacting genes: ACE2 CYTH3 DLG4 DOCK1 FYN GABBR2 GRM1 GRM2 GRM3 GRM5 RPS6KA1 SRC
Entrez ID		9265	160622
HPRD ID		05469	17077
Ensembl ID		ENSG00000008256	ENSG00000161835
Uniprot IDs		B7Z2V9 O43739	Q7Z6J2
PDB IDs		4KAX 6U3E 6U3G	2PNT
Enriched GO Terms of Interacting Partners?		Cell Cortex Cytoplasm Macrophage Activation Regulation Of Cellular Respiration Presynaptic Endocytosis Synaptic Vesicle Endocytosis Regulation Of Endocytosis Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission	Glutamate Receptor Signaling Pathway G Protein-coupled Glutamate Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway Glutamate Receptor Activity Chemical Synaptic Transmission Scaffold Protein Binding Trans-synaptic Signaling Synaptic Signaling Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Postsynaptic Membrane Negative Regulation Of Adenylate Cyclase Activity Glutamatergic Synapse Cell-cell Signaling Neuron Projection Astrocyte Projection Signaling Cell Communication Regulation Of Synaptic Transmission, Glutamatergic G Protein-coupled Receptor Signaling Pathway Neurotransmitter Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Group II Metabotropic Glutamate Receptor Activity Modulation Of Chemical Synaptic Transmission G Protein-coupled Receptor Activity Involved In Regulation Of Postsynaptic Membrane Potential G Protein-coupled Receptor Activity Adenylate Cyclase Inhibiting G Protein-coupled Glutamate Receptor Activity Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway Dendrite Regulation Of Cell Communication Regulation Of Signaling Plasma Membrane Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Phospholipase Activator Activity Postsynaptic Density Schaffer Collateral - CA1 Synapse Regulation Of Signal Transduction Postsynaptic Density Membrane Protein Tyrosine Kinase Activator Activity Amino Acid Transport Stimulatory C-type Lectin Receptor Signaling Pathway Phospholipase Binding Cellular Response To Lectin Signal Transduction Cellular Response To Platelet-derived Growth Factor Stimulus Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Response To Platelet-derived Growth Factor Dendritic Spine
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