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CYTH3

Description cytohesin 3
Image
GO Annotations Cellular Component
  • Golgi Membrane
  • Ruffle
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
  • Plasma Membrane
  • Adherens Junction
  • Bicellular Tight Junction
  • Membrane
  • Anchoring Junction
Molecular Function
  • Guanyl-nucleotide Exchange Factor Activity
  • Protein Binding
  • Phosphatidylinositol-3,4,5-trisphosphate Binding
  • Lipid Binding
Biological Process
  • Regulation Of ARF Protein Signal Transduction
  • Positive Regulation Of Cell Adhesion
  • Golgi Vesicle Transport
  • Establishment Of Epithelial Cell Polarity
Pathways
  • Intra-Golgi traffic
Drugs
  • Inositol 1,3,4,5-Tetrakisphosphate
  • Inositol-(1,3,4,5,6)-Pentakisphosphate
Diseases
GWAS
  • Asthma ( 27611488)
  • Body mass index ( 26426971)
  • Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)
  • Shigella-associated diarrhea ( 33649051)
Interacting Genes 10 interacting genes: ARFIP2 CALCOCO1 CNKSR1 CYTIP FRMD4B IFI35 ITSN1 PIK3CA SNCA TAMALIN
Entrez ID 9265
HPRD ID 05469
Ensembl ID ENSG00000008256
Uniprot IDs B7Z2V9 O43739
PDB IDs 4KAX 6U3E 6U3G
Enriched GO Terms of Interacting Partners?
  • Cell Cortex
  • Cytoplasm
  • Macrophage Activation
  • Regulation Of Cellular Respiration
  • Presynaptic Endocytosis
  • Synaptic Vesicle Endocytosis
  • Regulation Of Endocytosis
  • Response To Desipramine
  • Negative Regulation Of Norepinephrine Uptake
  • Phospholipase D Inhibitor Activity
  • Positive Regulation Of SNARE Complex Assembly
  • Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission
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