CYTH3 and CALCOCO1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CYTH3	CALCOCO1
Description		cytohesin 3	calcium binding and coiled-coil domain 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Ruffle Nucleoplasm Cytoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Membrane Anchoring Junction	Chromatin Nucleus Cytoplasm Cytosol
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Lipid Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Beta-catenin Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Regulation Of ARF Protein Signal Transduction Positive Regulation Of Cell Adhesion Golgi Vesicle Transport Establishment Of Epithelial Cell Polarity	Signal Transduction Positive Regulation Of Gene Expression Wnt Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Intra-Golgi traffic
Drugs		Inositol 1,3,4,5-Tetrakisphosphate Inositol-(1,3,4,5,6)-Pentakisphosphate
Diseases
GWAS		Asthma ( 27611488) Body mass index ( 26426971) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Shigella-associated diarrhea ( 33649051)	Panic disorder ( 19165232) Toenail selenium levels ( 25343990) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		10 interacting genes: ARFIP2 CALCOCO1 CNKSR1 CYTIP FRMD4B IFI35 ITSN1 PIK3CA SNCA TAMALIN	37 interacting genes: APP APTX ARNT BFSP2 CEP19 CREBBP CRYBA2 CTNNBL1 CWF19L2 CYTH3 DUSP13B ENKD1 EP300 FAM161A FOSL1 FXR1 GABARAPL1 GABARAPL2 GRIK2 IPP ISOC1 KRT15 MAPK1 MYH6 NDC80 NEDD4 PCBD1 POLR2A PRKAA2 RNF8 SH3GL3 SHANK3 SMURF1 SRPK2 TBC1D15 TBC1D17 ZMAT2
Entrez ID		9265	57658
HPRD ID		05469	13868
Ensembl ID		ENSG00000008256	ENSG00000012822
Uniprot IDs		B7Z2V9 O43739	Q9P1Z2
PDB IDs		4KAX 6U3E 6U3G
Enriched GO Terms of Interacting Partners?		Cell Cortex Cytoplasm Macrophage Activation Regulation Of Cellular Respiration Presynaptic Endocytosis Synaptic Vesicle Endocytosis Regulation Of Endocytosis Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission	Cytoplasm Regulation Of Long-term Neuronal Synaptic Plasticity Organelle Assembly Regulation Of Glycolytic Process Histone H3K27 Acetyltransferase Activity Regulation Of Neuronal Synaptic Plasticity Regulation Of Carbohydrate Catabolic Process Positive Regulation Of Glycolytic Process Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Cellular Response To Nutrient Levels Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Nucleoplasm Intracellular Signal Transduction Ciliary Basal Body Positive Regulation Of ATP Metabolic Process Regulation Of Synaptic Plasticity Regulation Of Tubulin Deacetylation Regulation Of Long-term Synaptic Potentiation Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Generation Of Precursor Metabolites And Energy Cellular Response To Nitrogen Starvation Regulation Of Protein Deacetylation Positive Regulation Of Synaptic Transmission Negative Regulation Of Long-term Synaptic Potentiation N-terminal Protein Amino Acid Acetylation Cellular Response To Stress Peptidyl-lysine Acetylation Intracellular Signaling Cassette Positive Regulation Of Small Molecule Metabolic Process Cytosol Damaged DNA Binding Prp19 Complex Phosphatidylethanolamine Binding Regulation Of Plasma Membrane Bounded Cell Projection Organization Positive Regulation Of Neuron Apoptotic Process Regulation Of Cellular Response To Heat Ubiquitin Protein Ligase Binding Regulation Of Cell Projection Organization Chromatin Binding Organelle Organization Scaffold Protein Binding Regulation Of Synaptic Transmission, Glutamatergic Response To Nutrient Levels GABA Receptor Binding Regulation Of Small Molecule Metabolic Process Cellular Response To Starvation
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