FNDC11 and ARL5B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FNDC11	ARL5B
Description		fibronectin type III domain containing 11	ARF like GTPase 5B
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Trans-Golgi Network
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process		Intracellular Protein Transport Vesicle-mediated Transport Protein Localization To Golgi Membrane
Pathways
Drugs			Guanosine-5'-Diphosphate
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Colorectal or endometrial cancer ( 26621817) Coronary artery disease in type 1 diabetes ( 29695241) Hepatitis C (spontaneous viral clearance) ( 33119750) Postoperative atrial fibrillation in coronary artery bypass grafting surgery ( 26385043) Suicide attempts in major depressive disorder ( 31164008)
Interacting Genes		44 interacting genes: AP1B1 ARL5B CALCOCO2 CCDC102B CCDC85B CDA CDCA4 CDKN1A CERCAM CINP COG6 FAM9B GOLGA2 GPBP1 HGS HMBOX1 ID2 KRT34 KRT40 KRTAP19-6 LZTS2 MAGEA12 MDFI MGAT5B MIS18A MTUS2 PDLIM7 PSMA1 RBPMS REL RNF125 SCNM1 SERTAD1 SMN1 SMN2 SORBS3 SSX2IP TRAF2 TRIM27 UBQLN2 ZBED1 ZNF48 ZNRD2 ZRANB1	2 interacting genes: FNDC11 SMAD4
Entrez ID		79025	221079
HPRD ID		14682	12328
Ensembl ID		ENSG00000125531	ENSG00000165997
Uniprot IDs		Q9BVV2	B0YIW9 Q96KC2
PDB IDs			1YZG
Enriched GO Terms of Interacting Partners?		Protein Binding Identical Protein Binding Cytoplasm	Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis Activin Responsive Factor Complex Left Ventricular Cardiac Muscle Tissue Morphogenesis Gonad Morphogenesis Nephrogenic Mesenchyme Morphogenesis Metanephric Mesenchyme Morphogenesis SMAD Protein Complex Positive Regulation Of Luteinizing Hormone Secretion Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Atrioventricular Valve Formation Sebaceous Gland Development Heteromeric SMAD Protein Complex Formation Of Anatomical Boundary Brainstem Development Mesendoderm Development Sulfate Binding Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of Transforming Growth Factor Beta2 Production Endocardial Cell Differentiation Atrioventricular Canal Development Somite Rostral/caudal Axis Specification Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Cardiac Muscle Cell Differentiation Endothelial Cell Activation Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Negative Regulation Of Cardiocyte Differentiation Secondary Palate Development Filamin Binding Neural Crest Cell Differentiation Heart Valve Formation Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Cardiac Muscle Cell Apoptotic Process I-SMAD Binding Cardiac Conduction System Development Interleukin-6-mediated Signaling Pathway Gastrulation With Mouth Forming Second Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of Cardiac Muscle Cell Differentiation Seminiferous Tubule Development Regulation Of Hair Follicle Development Regulation Of Extracellular Matrix Assembly Uterus Development Female Gonad Development Positive Regulation Of Extracellular Matrix Organization Outflow Tract Septum Morphogenesis SMAD Protein Signal Transduction Regulation Of Hair Cycle
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