CD8A and CACYBP

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CD8A	CACYBP
Gene Name		CD8a molecule	calcyclin binding protein
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane T Cell Receptor Complex	Nuclear Envelope Lumen Nucleoplasm Cytoplasm Beta-catenin Destruction Complex Neuron Projection Cell Body Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Coreceptor Activity Protein Kinase Binding MHC Class I Protein Binding Protein Homodimerization Activity	Protein Binding Protein Homodimerization Activity
	Biological Process	T Cell Mediated Immunity Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Antigen Processing And Presentation T Cell Activation Cytotoxic T Cell Differentiation Regulation Of Immune Response Positive Regulation Of Calcium-mediated Signaling Defense Response To Virus	Aging Positive Regulation Of DNA Replication Cardiac Muscle Cell Differentiation Response To Growth Hormone Negative Regulation Of Cell Death Cellular Response To Calcium Ion
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: B2M CACYBP CD3D CD59 CD8B CDK1 HLA-A HLA-B HLA-C HLA-E HLA-G LAT LCK LGALS1 PTPRC SREK1 SRSF1	13 interactors: CD8A DYT10 MAPK1 NGFRAP1 PINX1 S100A1 S100A12 S100A6 S100B S100P SIAH1 SIAH2 SKP1
Entrez ID		925	27101
HPRD ID		01737	07316
Ensembl ID		ENSG00000153563	ENSG00000116161
Uniprot IDs		P01732 Q6ZVS2 Q8TAW8	Q9HB71
PDB IDs		1AKJ 1CD8 1Q69 2HP4 3QZW	1X5M 2A25 2A26
Enriched GO Terms of Interacting Partners?		Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Positive Regulation Of T Cell Mediated Cytotoxicity Regulation Of T Cell Mediated Cytotoxicity Regulation Of Immune Response Positive Regulation Of Immune System Process Positive Regulation Of Leukocyte Mediated Cytotoxicity Regulation Of Immune System Process Positive Regulation Of T Cell Mediated Immunity Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Immune Response Positive Regulation Of Adaptive Immune Response Immune System Process Immune Response Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Regulation Of Adaptive Immune Response Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Interferon-gamma-mediated Signaling Pathway Regulation Of T Cell Activation Innate Immune Response Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Cellular Response To Interferon-gamma Positive Regulation Of T Cell Activation Regulation Of Cell-cell Adhesion Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Lymphocyte Activation Defense Response Response To Interferon-gamma Antigen Processing And Presentation Of Endogenous Antigen Positive Regulation Of Cell-cell Adhesion Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Protection From Natural Killer Cell Mediated Cytotoxicity Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Regulation Of Cell Activation Response To Type I Interferon Positive Regulation Of Cell Activation Antigen Processing And Presentation Of Peptide Antigen Regulation Of Defense Response To Virus By Virus Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Cell Adhesion Regulation Of Cell Adhesion Cell Surface Receptor Signaling Pathway Lymphocyte Activation Antigen Processing And Presentation Cell Activation Negative Regulation Of Immune Response Leukocyte Activation T Cell Aggregation T Cell Activation	Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Positive Regulation Of Intracellular Signal Transduction Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Neuron Development Response To Stimulus Cell Morphogenesis Neuron Differentiation Cell Projection Organization Chemotaxis Locomotion Positive Regulation Of Signal Transduction Cell Cycle Nervous System Development Movement Of Cell Or Subcellular Component Cytotoxic T Cell Differentiation Regulation Of Catalytic Activity Multicellular Organismal Development Generation Of Neurons Neurogenesis Axon Guidance Cellular Response To Stimulus Positive Regulation Of Voltage-gated Calcium Channel Activity MAPK Import Into Nucleus Apoptotic Process Regulation Of Intracellular Signal Transduction Programmed Cell Death Regulation Of Signal Transduction Cell Development Response To External Stimulus Cell Death Death Developmental Process Ubiquitin-dependent Protein Catabolic Process System Development Positive Regulation Of Cellular Protein Metabolic Process Modification-dependent Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Skeletal Muscle Cell Differentiation Regulation Of Golgi Inheritance Regulation Of Protein Stability Regulation Of Signaling Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Positive Regulation Of Transferase Activity
Tagcloud ?		anthracycline assignment bcs carboplatin cb ccl5 cd21 cd80 ctla4 cxcl13 cxcl9 foxp3 geparsixto hierarchic histopathologic ido1 igkc immunogenicity immunologic immunologically infiltrating lpbc ors pmcb standardization taxane tils tn univariable	3months 60s brains brdu bromodeoxyuridine calcyclin candidates comparative diphosphate disabilities ds dysregulated e14 embryos eminence fingerprinting ganglionic ndpk nucleoside p0 pk postnatal proteomic pyruvate rplp0 spots tk transketolase ts1cje
Tagcloud (Difference) ?		anthracycline assignment bcs carboplatin cb ccl5 cd21 cd80 ctla4 cxcl13 cxcl9 foxp3 geparsixto hierarchic histopathologic ido1 igkc immunogenicity immunologic immunologically infiltrating lpbc ors pmcb standardization taxane tils tn univariable	3months 60s brains brdu bromodeoxyuridine calcyclin candidates comparative diphosphate disabilities ds dysregulated e14 embryos eminence fingerprinting ganglionic ndpk nucleoside p0 pk postnatal proteomic pyruvate rplp0 spots tk transketolase ts1cje
Tagcloud (Intersection) ?