CACYBP and S100A1

Number of citations of the paper that reports this interaction (PMID 12042313)
20

Data Source:
HPRD (in vivo)

		CACYBP	S100A1
Gene Name		calcyclin binding protein	S100 calcium binding protein A1
Image
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Lumen Nucleoplasm Cytoplasm Beta-catenin Destruction Complex Neuron Projection Cell Body Extracellular Vesicular Exosome	Nucleus Sarcoplasmic Reticulum Z Disc M Band Neuron Projection Protein Complex
	Molecular Function	Protein Binding Protein Homodimerization Activity	Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding ATPase Binding
	Biological Process	Aging Positive Regulation Of DNA Replication Cardiac Muscle Cell Differentiation Response To Growth Hormone Negative Regulation Of Cell Death Cellular Response To Calcium Ion	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Heart Contraction Substantia Nigra Development Intracellular Signal Transduction Positive Regulation Of Voltage-gated Calcium Channel Activity
Pathways
Drugs			Olopatadine
Diseases
GWAS
Protein-Protein Interactions		13 interactors: CD8A DYT10 MAPK1 NGFRAP1 PINX1 S100A1 S100A12 S100A6 S100B S100P SIAH1 SIAH2 SKP1	24 interactors: ACTA1 AGER ANXA6 ATP2A2 CACYBP CAPZA1 DES FKBP4 GFAP GJA1 MDM2 NIF3L1 PGM1 PLB1 PLEKHF2 PLN PPID PYGM RYR1 S100A2 S100A4 S100B S100P SYN1
Entrez ID		27101	6271
HPRD ID		07316	01489
Ensembl ID		ENSG00000116161	ENSG00000160678
Uniprot IDs		Q9HB71	P23297
PDB IDs		1X5M 2A25 2A26	2L0P 2LHL 2LLS 2LLT 2LLU 2LP2 2LP3 2LUX
Enriched GO Terms of Interacting Partners?		Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Positive Regulation Of Intracellular Signal Transduction Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Neuron Development Response To Stimulus Cell Morphogenesis Neuron Differentiation Cell Projection Organization Chemotaxis Locomotion Positive Regulation Of Signal Transduction Cell Cycle Nervous System Development Movement Of Cell Or Subcellular Component Cytotoxic T Cell Differentiation Regulation Of Catalytic Activity Multicellular Organismal Development Generation Of Neurons Neurogenesis Axon Guidance Cellular Response To Stimulus Positive Regulation Of Voltage-gated Calcium Channel Activity MAPK Import Into Nucleus Apoptotic Process Regulation Of Intracellular Signal Transduction Programmed Cell Death Regulation Of Signal Transduction Cell Development Response To External Stimulus Cell Death Death Developmental Process Ubiquitin-dependent Protein Catabolic Process System Development Positive Regulation Of Cellular Protein Metabolic Process Modification-dependent Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Skeletal Muscle Cell Differentiation Regulation Of Golgi Inheritance Regulation Of Protein Stability Regulation Of Signaling Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Positive Regulation Of Transferase Activity	Muscle System Process Response To Abiotic Stimulus Regulation Of Cardiac Muscle Cell Contraction Regulation Of Muscle Contraction Regulation Of Heart Contraction Regulation Of Cardiac Muscle Cell Membrane Potential Protein Complex Assembly Sarcoplasmic Reticulum Calcium Ion Transport Regulation Of Cardiac Muscle Contraction Muscle Contraction Relaxation Of Cardiac Muscle Regulation Of Striated Muscle Contraction Glycogen Catabolic Process Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Polysaccharide Catabolic Process Calcium Ion Transport Relaxation Of Muscle Striated Muscle Tissue Development Negative Regulation Of Heart Contraction Skeletal Muscle Fiber Development Response To Hormone Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Response To Metal Ion Muscle Tissue Development Cellular Component Assembly Myotube Cell Development Regulation Of Cellular Localization Cellular Carbohydrate Catabolic Process Regulation Of The Force Of Heart Contraction Actin-myosin Filament Sliding Muscle Filament Sliding Response To Wounding Regulation Of Ion Homeostasis Regulation Of Actin Filament-based Process Cellular Metal Ion Homeostasis Cellular Response To Alkaloid Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Astrocyte Differentiation Cytosolic Calcium Ion Homeostasis Cellular Cation Homeostasis Actin-mediated Cell Contraction Cellular Ion Homeostasis Response To Peptide Hormone Cardiac Conduction Tissue Development Negative Regulation Of Striated Muscle Tissue Development Steroid Hormone Receptor Complex Assembly Calcium Ion Transport From Cytosol To Endoplasmic Reticulum Positive Regulation Of Schwann Cell Proliferation
Tagcloud ?		3months 60s brains brdu bromodeoxyuridine calcyclin candidates comparative diphosphate disabilities ds dysregulated e14 embryos eminence fingerprinting ganglionic ndpk nucleoside p0 pk postnatal proteomic pyruvate rplp0 spots tk transketolase ts1cje	ablation ad ascertain astrocytosis burden collectively demonstration detrimental elucidated gfap gsk3beta iba1 identifies indirectly microgliosis modulates neuroinflammation normalizing pathobiology pc12 plaque po4 psapp ryanodine ryr sensor twelve undetectable uses
Tagcloud (Difference) ?		3months 60s brains brdu bromodeoxyuridine calcyclin candidates comparative diphosphate disabilities ds dysregulated e14 embryos eminence fingerprinting ganglionic ndpk nucleoside p0 pk postnatal proteomic pyruvate rplp0 spots tk transketolase ts1cje	ablation ad ascertain astrocytosis burden collectively demonstration detrimental elucidated gfap gsk3beta iba1 identifies indirectly microgliosis modulates neuroinflammation normalizing pathobiology pc12 plaque po4 psapp ryanodine ryr sensor twelve undetectable uses
Tagcloud (Intersection) ?