CACYBP and S100A1

Number of citations of the paper that reports this interaction (PubMedID 12042313)
0

Data Source:
HPRD (in vivo)

		CACYBP	S100A1
Description		calcyclin binding protein	S100 calcium binding protein A1
Image
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Lumen Nucleoplasm Cytoplasm Cytosol SCF Ubiquitin Ligase Complex Beta-catenin Destruction Complex Cell Body Extracellular Exosome	Extracellular Region Nucleus Nucleoplasm Cytoplasm Mitochondrion Golgi Apparatus Cytosol Sarcoplasmic Reticulum Z Disc M Band A Band I Band Protein-containing Complex
	Molecular Function	Protein Binding Tubulin Binding Protein Domain Specific Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity S100 Protein Binding	Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Metal Ion Binding Calcium-dependent Protein Binding ATPase Binding
	Biological Process	Heart Development Positive Regulation Of DNA Replication Cardiac Muscle Cell Differentiation Response To Growth Hormone Cellular Response To Calcium Ion Cellular Response To Leukemia Inhibitory Factor	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Heart Contraction Substantia Nigra Development Intracellular Signal Transduction Vasodilation Positive Regulation Of Sprouting Angiogenesis
Pathways			ER-Phagosome pathway MyD88:MAL(TIRAP) cascade initiated on plasma membrane MyD88 deficiency (TLR2/4) IRAK4 deficiency (TLR2/4) Regulation of TLR by endogenous ligand
Drugs			Olopatadine
Diseases
GWAS
Interacting Genes		22 interacting genes: BEX3 CCR2 CD8A CEBPA ERBB2 FBXO7 HSP90AA1 HSP90B1 MAPK1 NPM1 PEA15 PINX1 PRKCA S100A1 S100A12 S100A6 S100B S100P SIAH1 SIAH2 SKP1 SNCA	36 interacting genes: ACTA1 AGER ANXA6 ATP2A2 BEX3 BIK CACYBP CAPZA1 CEP20 CLCF1 CNTF CTF1 DES FKBP4 GFAP GJA1 IFNB1 IL11 MDM2 NIF3L1 PGM1 PLB1 PLEKHF2 PLN PPID PYGM REL RYR1 S100A2 S100A3 S100A4 S100B S100P S100Z SYN1 TP53
Entrez ID		27101	6271
HPRD ID		07316	01489
Ensembl ID		ENSG00000116161	ENSG00000160678
Uniprot IDs		Q9HB71	A0A0S2Z4H2 P23297
PDB IDs		1X5M 2A25 2A26	2L0P 2LHL 2LLS 2LLT 2LLU 2LP2 2LP3 2LUX 2M3W 5K89
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Regulation Of Apoptotic Process Calcium-dependent Protein Binding Regulation Of Programmed Cell Death Regulation Of Protein Stability Protein Catabolic Process S100 Protein Binding Calcium Ion Binding Regulation Of Protein Metabolic Process Regulation Of Protein Modification Process Apoptotic Process Positive Regulation Of Defense Response Cell Death Programmed Cell Death Perinuclear Region Of Cytoplasm Proteasomal Protein Catabolic Process Positive Regulation Of Inflammatory Response Protein-containing Complex Regulation Of Protein Ubiquitination Amyloid Fibril Formation Negative Regulation Of Apoptotic Process Nucleus Negative Regulation Of Programmed Cell Death Regulation Of Post-translational Protein Modification Regulation Of Immune System Process Proteolysis Involved In Protein Catabolic Process Protein Homodimerization Activity Positive Regulation Of Protein Localization To Nucleolus Tau Protein Binding Regulation Of Signal Transduction Cytosol Regulation Of Biological Quality Macromolecule Catabolic Process Positive Regulation Of Synaptic Transmission Positive Regulation Of Cell Communication Positive Regulation Of Signaling Sperm Plasma Membrane Long-term Synaptic Potentiation ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Regulation Of Defense Response Intracellular Signaling Cassette Neuronal Cell Body Regulation Of Protein Localization To Nucleolus Nucleoplasm RAGE Receptor Binding Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Cell Population Proliferation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Calcium-dependent Protein Binding S100 Protein Binding Transition Metal Ion Binding Identical Protein Binding Calcium Ion Binding Calcium Ion-transporting ATPase Complex Negative Regulation Of Blood Circulation Regulation Of Blood Circulation Regulation Of System Process Cell Surface Receptor Signaling Pathway Via JAK-STAT Cellular Response To Actinomycin D Cell Surface Receptor Signaling Pathway Via STAT Cell Body Response To Actinomycin D Cellular Response To UV-C Ciliary Neurotrophic Factor Receptor Binding Sarcoplasmic Reticulum Membrane Positive Regulation Of Cell Population Proliferation Regulation Of Cardiac Muscle Cell Membrane Potential Cytokine Activity Intercalated Disc Muscle System Process Positive Regulation Of Peptidyl-tyrosine Phosphorylation Cellular Response To Antibiotic Negative Regulation Of ATP-dependent Activity RAGE Receptor Binding Developmental Process Relaxation Of Cardiac Muscle Response To Hypoxia Cell Activation Response To UV-C Sarcoplasmic Reticulum Response To Decreased Oxygen Levels Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Sarcoplasmic Reticulum Calcium Ion Transport Modulation Of Chemical Synaptic Transmission Regulation Of Apoptotic Process Regulation Of Peptidyl-tyrosine Phosphorylation Response To Oxygen Levels Astrocyte Activation Astrocyte Development Intracellular Calcium Ion Homeostasis Regulation Of Programmed Cell Death Regulation Of Heart Contraction Relaxation Of Muscle Cellular Response To UV Negative Regulation Of Heart Contraction Circadian Behavior Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Rhythmic Behavior
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