SERF1B and ELOVL7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SERF1B	ELOVL7
Description		small EDRK-rich factor 1B	ELOVL fatty acid elongase 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Protein-containing Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding Fatty Acid Elongase Activity Transferase Activity
	Biological Process	Nervous System Development Protein Destabilization Amyloid Fibril Formation	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process
Pathways			Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS			Age at first sexual intercourse ( 34211149) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cortical surface area ( 32963231) Cortical surface area (MOSTest) ( 32665545) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean platelet volume ( 32888494 27863252) Multiple system atrophy ( 27629089) Parkinson's disease ( 32201043 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Subcortical volume (MOSTest) ( 32665545) Working memory ( 31598132)
Interacting Genes		12 interacting genes: ABHD16A AQP6 CERS4 CRB3 ELOVL4 ELOVL7 GPR152 REEP4 RNASEK TIMMDC1 TMEM14B TMX2	12 interacting genes: ADGRE2 DTNBP1 EMP3 LRCH4 RTP2 SERF1A SERF1B SLC41A1 SYNJ2BP TMEM14C UBE2J2 VAMP1
Entrez ID		728492	79993
HPRD ID			18700
Ensembl ID		ENSG00000205572	ENSG00000164181
Uniprot IDs		O75920	A1L3X0 D6RHD0
PDB IDs			6Y7F
Enriched GO Terms of Interacting Partners?		Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid Membrane Fatty Acid Derivative Metabolic Process Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Sphingolipid Biosynthetic Process Long-chain Fatty-acyl-CoA Biosynthetic Process Amide Biosynthetic Process Long-chain Fatty-acyl-CoA Metabolic Process Sphingolipid Metabolic Process Fatty-acyl-CoA Biosynthetic Process Mitochondrial Membrane Very Long-chain Fatty Acid Metabolic Process Membrane Lipid Metabolic Process Unsaturated Fatty Acid Biosynthetic Process Endoplasmic Reticulum Membrane Fatty Acid Derivative Biosynthetic Process Nitrate Transmembrane Transporter Activity PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Acyl-CoA Metabolic Process Unsaturated Fatty Acid Metabolic Process Sulfur Compound Biosynthetic Process Subapical Complex Endoplasmic Reticulum Fatty Acid Biosynthetic Process Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Monoacylglycerol Catabolic Process Sphingosine N-acyltransferase Activity Lipid Metabolic Process Lipid Biosynthetic Process Monoatomic Anion Channel Activity Renal Water Transport Ammonium Channel Activity Disulfide Oxidoreductase Activity Ammonium Transmembrane Transport Mitotic Nuclear Membrane Reassembly Golgi Lumen Acidification Vacuolar Proton-transporting V-type ATPase, V0 Domain G Protein-coupled Photoreceptor Activity Monoacylglycerol Lipase Activity Receptor-mediated Endocytosis Of Virus By Host Cell Water Channel Activity Endosomal Lumen Acidification
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