DAPL1 and TSR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DAPL1	TSR2
Description		death associated protein like 1	TSR2 ribosome maturation factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	Protein Binding Translation Repressor Activity Translation Initiation Factor Binding Ribosome Binding	Protein Binding
	Biological Process	Apoptotic Process Cell Population Proliferation Gene Expression Negative Regulation Of Autophagy Cell Differentiation Apoptotic Signaling Pathway Ribosome Hibernation Negative Regulation Of CD8-positive, Alpha-beta T Cell Activation	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease in APOE e4+ carriers ( 25778476) LDL cholesterol levels x long total sleep time interaction (1df test) ( 31719535) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Obesity-related traits ( 23251661)	Prostate cancer ( 31562322)
Interacting Genes		7 interacting genes: FHL2 FNDC3B LSM1 TRIM55 TRIM63 TSR2 ZIC1	24 interacting genes: CAMK2A CMIP CREB5 DAPL1 DISC1 EXOSC3 GABARAP GABARAPL2 GAS2L3 GSC2 KIF16B KIFC3 LAMB2 MAP1LC3C MEOX2 PIAS2 PRKAB2 PTRHD1 RBM48 RPS26 SPATC1L ZBTB9 ZNF474 ZNF620
Entrez ID		92196	90121
HPRD ID		18709	06493
Ensembl ID		ENSG00000163331	ENSG00000158526
Uniprot IDs		A0PJW8 M1E9T5	Q969E8
PDB IDs
Enriched GO Terms of Interacting Partners?			Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Microtubule Microtubule Binding Kinesin Complex Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagosome GABA Receptor Binding Autophagosome Assembly Cellular Response To Nutrient Levels Autophagosome Organization Phospholipid Binding Ubiquitin Protein Ligase Binding Protein-containing Complex Disassembly
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