TSR2 and GAS2L3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TSR2	GAS2L3
Description		TSR2 ribosome maturation factor	growth arrest specific 2 like 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Cytoskeleton Microtubule Actin Cytoskeleton Microtubule Cytoskeleton
	Molecular Function	Protein Binding	Actin Binding Protein Binding Microtubule Binding Actin Filament Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing	Microtubule Cytoskeleton Organization Actin Cytoskeleton Organization Actin Crosslink Formation
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 31562322)	Squamous cell carcinoma ( 23341777)
Interacting Genes		24 interacting genes: CAMK2A CMIP CREB5 DAPL1 DISC1 EXOSC3 GABARAP GABARAPL2 GAS2L3 GSC2 KIF16B KIFC3 LAMB2 MAP1LC3C MEOX2 PIAS2 PRKAB2 PTRHD1 RBM48 RPS26 SPATC1L ZBTB9 ZNF474 ZNF620	7 interacting genes: AURKB BIRC5 CDCA8 CDK1 FNDC3B MFHAS1 TSR2
Entrez ID		90121	283431
HPRD ID		06493	13568
Ensembl ID		ENSG00000158526	ENSG00000139354
Uniprot IDs		Q969E8	B3KTH9 G3V1N3 Q86XJ1
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Microtubule Microtubule Binding Kinesin Complex Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagosome GABA Receptor Binding Autophagosome Assembly Cellular Response To Nutrient Levels Autophagosome Organization Phospholipid Binding Ubiquitin Protein Ligase Binding Protein-containing Complex Disassembly	Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Metaphase Plate Congression Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Chromosome Segregation Chromosome Passenger Complex Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Mitotic Spindle Midzone Assembly Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Spindle Midzone Assembly Positive Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Cytokinesis Positive Regulation Of Cell Cycle Checkpoint Regulation Of Sister Chromatid Segregation Positive Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Microtubule Cytoskeleton Organization Involved In Mitosis Spindle Midzone Regulation Of Chromosome Segregation Positive Regulation Of Chromosome Separation Midbody Spindle Microtubule Positive Regulation Of Cytokinesis Mitotic Spindle Assembly Spindle Cell Cycle G2/M Phase Transition Regulation Of Chromosome Organization Regulation Of Mitotic Sister Chromatid Separation Positive Regulation Of Cell Cycle Process Mitotic Cytokinesis Regulation Of Chromosome Separation Regulation Of Cytokinesis Positive Regulation Of Cell Cycle Positive Regulation Of Cell Division Mitotic Spindle Organization Cytoskeleton-dependent Cytokinesis Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Mitotic Cell Cycle Phase Transition Spindle Assembly Positive Regulation Of Mitotic Sister Chromatid Segregation Chromocenter Regulation Of Mitotic Nuclear Division Protein Localization To Kinetochore Regulation Of Cell Cycle Phase Transition Microtubule Cytoskeleton Organization Cell Division Mitotic Cell Cycle Regulation Of Nuclear Division Regulation Of Mitotic Cell Cycle Spindle Organization
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