TSR2 and PTRHD1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		TSR2	PTRHD1
Name		TSR2 ribosome maturation factor	peptidyl-tRNA hydrolase domain containing 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Mitochondrion
	Molecular Function	Protein Binding	Peptidyl-tRNA Hydrolase Activity Protein Binding Hydrolase Activity
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing	None
GWAS		Prostate cancer ( 31562322 )	Body mass index ( 26426971 ) Body mass index (age <50) ( 26426971 ) Body mass index (age>50) ( 26426971 ) Body mass index x sex x age interaction (4df test) ( 26426971 )
Interacting Genes		24 interacting genes: CAMK2A CMIP CREB5 DAPL1 DISC1 EXOSC3 GABARAP GABARAPL2 GAS2L3 GSC2 KIF16B KIFC3 LAMB2 MAP1LC3C MEOX2 PIAS2 PRKAB2 PTRHD1 RBM48 RPS26 SPATC1L ZBTB9 ZNF474 ZNF620	2 interacting genes: RPA4 TSR2
Entrez ID		90121	391356
HPRD ID		06493	18406
Ensembl ID		ENSG00000158526	ENSG00000184924
Uniprot IDs		Q969E8	Q6GMV3
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Microtubule Microtubule Binding Kinesin Complex Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagosome GABA Receptor Binding Autophagosome Assembly Cellular Response To Nutrient Levels Autophagosome Organization Phospholipid Binding Ubiquitin Protein Ligase Binding Protein-containing Complex Disassembly	Nuclear DNA Replication DNA Replication Factor A Complex DNA Replication Initiation Telomeric DNA Binding Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of SSU-rRNA Nucleotide-excision Repair DNA-templated DNA Replication