TSR2 and DAPL1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		TSR2	DAPL1
Name		TSR2 ribosome maturation factor	death associated protein like 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	Protein Binding	Protein Binding Translation Repressor Activity Translation Initiation Factor Binding Ribosome Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing	Apoptotic Process Cell Population Proliferation Gene Expression Negative Regulation Of Autophagy Cell Differentiation Apoptotic Signaling Pathway Ribosome Hibernation Negative Regulation Of CD8-positive, Alpha-beta T Cell Activation
GWAS		Prostate cancer ( 31562322 )	Alzheimer's disease in APOE e4+ carriers ( 25778476 ) LDL cholesterol levels x long total sleep time interaction (1df test) ( 31719535 ) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535 ) Obesity-related traits ( 23251661 )
Interacting Genes		24 interacting genes: CAMK2A CMIP CREB5 DAPL1 DISC1 EXOSC3 GABARAP GABARAPL2 GAS2L3 GSC2 KIF16B KIFC3 LAMB2 MAP1LC3C MEOX2 PIAS2 PRKAB2 PTRHD1 RBM48 RPS26 SPATC1L ZBTB9 ZNF474 ZNF620	7 interacting genes: FHL2 FNDC3B LSM1 TRIM55 TRIM63 TSR2 ZIC1
Entrez ID		90121	92196
HPRD ID		06493	18709
Ensembl ID		ENSG00000158526	ENSG00000163331
Uniprot IDs		Q969E8	A0PJW8 M1E9T5
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Microtubule Microtubule Binding Kinesin Complex Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagosome GABA Receptor Binding Autophagosome Assembly Cellular Response To Nutrient Levels Autophagosome Organization Phospholipid Binding Ubiquitin Protein Ligase Binding Protein-containing Complex Disassembly	None