TSR2 and CMIP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TSR2	CMIP
Description		TSR2 ribosome maturation factor	c-Maf inducing protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing	In Utero Embryonic Development
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 31562322)	A body shape index ( 34021172) Adiponectin levels ( 22479202 31178129 24105470) Adult body size ( 32376654) Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065) Age-related cataracts ( 25352737) Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Appendicular lean mass ( 33097823) Body size at age 10 ( 32376654) Cadmium levels ( 26025379) Dehydroepiandrosterone sulphate levels ( 28887542) Diastolic blood pressure ( 27841878 28135244) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) HDL cholesterol ( 30275531 25961943 24097068 20686565) HDL cholesterol levels ( 28334899 30698716 32203549) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Heel bone mineral density ( 28869591 30598549) Height ( 31562340) Hematology traits ( 30576415) High density lipoprotein cholesterol levels ( 33339817 29403010) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Lymphocyte percentage of white cells ( 32888494) Mean spheric corpuscular volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (beta blocking agents) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Menarche (age at onset) ( 23667675) Metabolic syndrome ( 31589552) Neuritic plaque ( 31497858) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Pursuit maintenance gain ( 29064472) Systolic blood pressure ( 27841878) Triglyceride levels ( 30698716 32154731 32203549) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 30275531) Type 2 diabetes ( 32499647 22158537 30297969 30054458 28869590 28566273) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500) White blood cell count ( 32888494)
Interacting Genes		24 interacting genes: CAMK2A CMIP CREB5 DAPL1 DISC1 EXOSC3 GABARAP GABARAPL2 GAS2L3 GSC2 KIF16B KIFC3 LAMB2 MAP1LC3C MEOX2 PIAS2 PRKAB2 PTRHD1 RBM48 RPS26 SPATC1L ZBTB9 ZNF474 ZNF620	5 interacting genes: FLNA MTNR1A TRIM54 TSR2 ZC4H2
Entrez ID		90121	80790
HPRD ID		06493	10839
Ensembl ID		ENSG00000158526	ENSG00000153815
Uniprot IDs		Q969E8	A0A087WU05 Q8IY22
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Microtubule Microtubule Binding Kinesin Complex Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagosome GABA Receptor Binding Autophagosome Assembly Cellular Response To Nutrient Levels Autophagosome Organization Phospholipid Binding Ubiquitin Protein Ligase Binding Protein-containing Complex Disassembly	Glycoprotein Ib-IX-V Complex Regulation Of Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Regulation Of DNA-binding Transcription Factor Activity Fc-gamma Receptor I Complex Binding Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Formation Of Radial Glial Scaffolds Tubulin Deacetylation Z Disc Myb Complex Establishment Of Sertoli Cell Barrier Melatonin Receptor Activity Noradrenergic Neuron Development Protein Localization To Bicellular Tight Junction Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential
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