NEUROG1 and RUNX1T1

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		NEUROG1	RUNX1T1
Gene Name		neurogenin 1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Perikaryon	Nucleoplasm Cytoplasm Mitochondrion Nuclear Matrix
	Molecular Function	Transcription Factor Binding Transcription Factor Activity DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Dimerization Activity E-box Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Nervous System Development Neuron Differentiation Positive Regulation Of Exit From Mitosis Inner Ear Morphogenesis Cell Fate Commitment Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity	Generation Of Precursor Metabolites And Energy Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CBFA2T2 CREBBP RUNX1T1 SMAD1 TARBP2 TCF4	53 interactors: ABI3 ATN1 BCL6 BRCA1 C19orf57 CBFA2T3 CCDC36 CEP170P1 CPSF7 CREB3L1 DNMT1 EFHC2 EPS8 ETS1 GFI1 GSE1 HDAC1 HDAC3 HDAC8 HOMER3 HSP90AA1 ID1 ID3 KPNA1 KPNB1 LPXN LZTS2 MEOX2 MID2 NCOR1 NCOR2 NECAB2 NEUROG1 PCBD2 PRDM14 PRKAR2A SIN3A SPEN SPERT SPRY2 STX11 TAF9B TAL2 TCF12 TCF3 TCF4 TRIM42 UBQLN4 VDR WBP11 ZBTB16 ZMYM4 ZNF652
Entrez ID		4762	862
HPRD ID		03430	00590
Ensembl ID		ENSG00000181965	ENSG00000079102
Uniprot IDs		F1T0H3 Q92886	B2R6I9 Q06455
PDB IDs			1WQ6 2DJ8 2H7B 2KNH 2KYG 2OD1 2ODD 2PP4 4JOL
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Production Of MiRNAs Involved In Gene Silencing By MiRNA Regulation Of Transcription From RNA Polymerase II Promoter Gene Silencing By MiRNA Cellular Response To DsRNA Posttranscriptional Gene Silencing Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Silencing By RNA Positive Regulation Of Neurogenesis Response To DsRNA Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Development Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Neuron Differentiation Positive Regulation Of Gene Expression RNA Metabolic Process Gene Silencing Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Cell Differentiation Cellular Macromolecular Complex Assembly Gene Expression Embryonic Morphogenesis Fat Cell Differentiation Regulation Of Neurogenesis MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Cellular Component Assembly Negative Regulation Of Cell Differentiation Stem Cell Maintenance Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Targeting Of MRNA For Destruction Involved In RNA Interference N-terminal Peptidyl-lysine Acetylation Regulation Of Cell Development Positive Regulation Of Cell Differentiation	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of RNA Biosynthetic Process RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Heterocycle Metabolic Process Negative Regulation Of Gene Expression Cellular Aromatic Compound Metabolic Process Gene Expression Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cellular Process Multicellular Organismal Development Positive Regulation Of Macromolecule Biosynthetic Process Response To Organic Substance Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Embryo Development Cellular Metabolic Process Organ Development Developmental Process Anatomical Structure Development System Development Transcription Initiation From RNA Polymerase II Promoter Regulation Of Cell Differentiation Cellular Response To Organic Substance Rhythmic Process Organelle Organization Regulation Of Apoptotic Process
Tagcloud ?		appearance comprehending correlate epigenetic epigenetics etc foxg1 grik3 hand2 hox integrating islands luad methylated nkx6 pik3ca pik3r3 pou4f2 prkcb ptgdr raf1 rap1a refers stages subnetwork tlx3 ubc ultimate wise	accumulated aml aml201 cbfb cebpa chimeric clarify comprehensively cooperative cytogenetically cytogenetics dnmt3a exclusive flt3 impacts japan kit leukemianet mll myh11 npm1 precise ptd recurrently registered sole stratified translocations
Tagcloud (Difference) ?		appearance comprehending correlate epigenetic epigenetics etc foxg1 grik3 hand2 hox integrating islands luad methylated nkx6 pik3ca pik3r3 pou4f2 prkcb ptgdr raf1 rap1a refers stages subnetwork tlx3 ubc ultimate wise	accumulated aml aml201 cbfb cebpa chimeric clarify comprehensively cooperative cytogenetically cytogenetics dnmt3a exclusive flt3 impacts japan kit leukemianet mll myh11 npm1 precise ptd recurrently registered sole stratified translocations
Tagcloud (Intersection) ?