AGK and SNX4

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		AGK	SNX4
Gene Name		acylglycerol kinase	sorting nexin 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Membrane Intracellular Membrane-bounded Organelle	Cytoplasm Cytoplasmic Dynein Complex Plasma Membrane Membrane Extrinsic Component Of Membrane SNARE Complex Early Endosome Membrane Protein Complex
	Molecular Function	Ceramide Kinase Activity NAD+ Kinase Activity Diacylglycerol Kinase Activity ATP Binding Acylglycerol Kinase Activity	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Transferrin Receptor Binding Leptin Receptor Binding
	Biological Process	Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Glycerolipid Metabolic Process Ceramide Biosynthetic Process Lipid Phosphorylation	Protein Transport Vesicle Organization Endocytic Recycling Positive Regulation Of Histamine Secretion By Mast Cell
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: HCK PDLIM1 SNX4	15 interactors: AGK ARL6IP1 ATP6V0A1 BIN1 EGFR HIVEP1 INSR LEPR MAGEA6 PDGFRA PDGFRB PTPN5 SNX2 SNX6 SUPT5H
Entrez ID		55750	8723
HPRD ID		08554	09334
Ensembl ID			ENSG00000114520
Uniprot IDs		A4D1U5 Q53H12	O95219
PDB IDs
Enriched GO Terms of Interacting Partners?		Respiratory Burst After Phagocytosis Leukocyte Migration Involved In Immune Response Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Regulation Of Inflammatory Response Respiratory Burst Involved In Defense Response Regulation Of Vesicle-mediated Transport Regulation Of Podosome Assembly Positive Regulation Of Mast Cell Degranulation Respiratory Burst Positive Regulation Of Mast Cell Activation Positive Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Immune Response Positive Regulation Of Regulated Secretory Pathway Endocytic Recycling Regulation Of Defense Response To Virus By Virus Regulation Of Mast Cell Degranulation Regulation Of Immune Response Positive Regulation Of Immune System Process Regulation Of Mast Cell Activation Peptidyl-tyrosine Autophosphorylation Lipopolysaccharide-mediated Signaling Pathway Regulation Of Regulated Secretory Pathway Regulation Of Actin Cytoskeleton Reorganization Leukocyte Degranulation Regulated Secretory Pathway Positive Regulation Of Exocytosis Regulation Of Phagocytosis Defense Response To Gram-positive Bacterium Regulation Of Immune System Process	Metanephric Glomerular Capillary Formation Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Positive Regulation Of DNA Metabolic Process Positive Regulation Of Phospholipase C Activity Glomerular Capillary Formation Protein Autophosphorylation Positive Regulation Of DNA Replication Metanephric Glomerulus Vasculature Development Positive Regulation Of Phospholipase Activity Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Peptidyl-tyrosine Phosphorylation Metanephric Glomerulus Development Glomerulus Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of DNA Replication Positive Regulation Of ERK1 And ERK2 Cascade Retina Vasculature Development In Camera-type Eye Glomerulus Vasculature Development Cardiac Myofibril Assembly Cellular Response To Platelet-derived Growth Factor Stimulus Phosphatidylinositol-mediated Signaling Response To Platelet-derived Growth Factor Regulation Of Kinase Activity Digestive System Development Regulation Of Reactive Oxygen Species Metabolic Process Vascular Endothelial Growth Factor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of MAPK Cascade ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase Activity Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organonitrogen Compound Positive Regulation Of Kinase Activity Regulation Of Cellular Ketone Metabolic Process Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of ERK1 And ERK2 Cascade Response To Fibroblast Growth Factor Adrenal Gland Development Metanephric Nephron Development Regulation Of Peptidyl-tyrosine Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity Regulation Of Catalytic Activity
Tagcloud ?		acylglycerol anchorage biomarker brdu clinicopathologic clinicopathological colony demonstrating foxo1 gained herein ihc immunoblotting immunochemistry insights luciferase nodule oncogenic overexpressed overexpressing p21cip1 p27kip1 paired shorter tnm transactivity tumorigenicity valuable xenograft
Tagcloud (Difference) ?		acylglycerol anchorage biomarker brdu clinicopathologic clinicopathological colony demonstrating foxo1 gained herein ihc immunoblotting immunochemistry insights luciferase nodule oncogenic overexpressed overexpressing p21cip1 p27kip1 paired shorter tnm transactivity tumorigenicity valuable xenograft
Tagcloud (Intersection) ?