AGK and PDLIM1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		AGK	PDLIM1
Gene Name		acylglycerol kinase	PDZ and LIM domain 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Membrane Intracellular Membrane-bounded Organelle	Transcription Factor Complex Cytoplasm Cytoskeleton Focal Adhesion
	Molecular Function	Ceramide Kinase Activity NAD+ Kinase Activity Diacylglycerol Kinase Activity ATP Binding Acylglycerol Kinase Activity	Transcription Coactivator Activity Zinc Ion Binding
	Biological Process	Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Glycerolipid Metabolic Process Ceramide Biosynthetic Process Lipid Phosphorylation	Response To Hypoxia Regulation Of Transcription, DNA-templated Response To Oxidative Stress
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: HCK PDLIM1 SNX4	13 interactors: ACTN1 ACTN2 ACTN4 AGK GFAP MAPK6 PGS1 PITX2 RLIM RPS6KA5 STK35 SUPT4H1 VIM
Entrez ID		55750	9124
HPRD ID		08554	09326
Ensembl ID			ENSG00000107438
Uniprot IDs		A4D1U5 Q53H12	O00151
PDB IDs			1X62 2PKT
Enriched GO Terms of Interacting Partners?		Respiratory Burst After Phagocytosis Leukocyte Migration Involved In Immune Response Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Regulation Of Inflammatory Response Respiratory Burst Involved In Defense Response Regulation Of Vesicle-mediated Transport Regulation Of Podosome Assembly Positive Regulation Of Mast Cell Degranulation Respiratory Burst Positive Regulation Of Mast Cell Activation Positive Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Immune Response Positive Regulation Of Regulated Secretory Pathway Endocytic Recycling Regulation Of Defense Response To Virus By Virus Regulation Of Mast Cell Degranulation Regulation Of Immune Response Positive Regulation Of Immune System Process Regulation Of Mast Cell Activation Peptidyl-tyrosine Autophosphorylation Lipopolysaccharide-mediated Signaling Pathway Regulation Of Regulated Secretory Pathway Regulation Of Actin Cytoskeleton Reorganization Leukocyte Degranulation Regulated Secretory Pathway Positive Regulation Of Exocytosis Regulation Of Phagocytosis Defense Response To Gram-positive Bacterium Regulation Of Immune System Process	Protein Localization To Tight Junction Bergmann Glial Cell Differentiation Protein Localization To Cell Junction Platelet Degranulation Intermediate Filament Organization Actin Crosslink Formation Astrocyte Development Actin-myosin Filament Sliding Focal Adhesion Assembly Muscle Filament Sliding Platelet Activation Cell Junction Assembly Cell-cell Junction Organization Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Intermediate Filament-based Process Actin-mediated Cell Contraction Tight Junction Assembly Adherens Junction Assembly Actin Filament-based Process Positive Regulation Of Ion Transmembrane Transporter Activity Cell-substrate Junction Assembly Response To Wounding Positive Regulation Of Transporter Activity Actin Filament Bundle Assembly Actin Filament-based Movement Histone H2A-S1 Phosphorylation Subthalamic Nucleus Development Prolactin Secreting Cell Differentiation Random Inactivation Of X Chromosome Positive Regulation Of Schwann Cell Proliferation Superior Vena Cava Morphogenesis Apical Junction Assembly Exocytosis Positive Regulation Of Ion Transmembrane Transport Adherens Junction Organization Cell Proliferation Involved In Outflow Tract Morphogenesis Subthalamus Development Left Lung Morphogenesis Pulmonary Vein Morphogenesis Blood Coagulation Glial Cell Development Hemostasis Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Extraocular Skeletal Muscle Development Pulmonary Myocardium Development Positive Regulation Of Pinocytosis Left Lung Development Cell-cell Junction Assembly Negative Regulation Of Neuron Projection Development
Tagcloud ?		acylglycerol anchorage biomarker brdu clinicopathologic clinicopathological colony demonstrating foxo1 gained herein ihc immunoblotting immunochemistry insights luciferase nodule oncogenic overexpressed overexpressing p21cip1 p27kip1 paired shorter tnm transactivity tumorigenicity valuable xenograft
Tagcloud (Difference) ?		acylglycerol anchorage biomarker brdu clinicopathologic clinicopathological colony demonstrating foxo1 gained herein ihc immunoblotting immunochemistry insights luciferase nodule oncogenic overexpressed overexpressing p21cip1 p27kip1 paired shorter tnm transactivity tumorigenicity valuable xenograft
Tagcloud (Intersection) ?