MTMR6 and AMOTL2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MTMR6	AMOTL2
Gene Name		myotubularin related protein 6	angiomotin like 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Cytoplasm Cytosol	Cytosol Tight Junction Apical Plasma Membrane Cytoplasmic Vesicle Recycling Endosome
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Calcium-activated Potassium Channel Activity	Protein Binding Identical Protein Binding
	Biological Process	Protein Dephosphorylation Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Peptidyl-tyrosine Dephosphorylation Small Molecule Metabolic Process Potassium Ion Transmembrane Transport	Wnt Signaling Pathway Hippo Signaling
Pathways		Synthesis of PIPs at the plasma membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism	Signaling by Hippo
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: AMOTL2 MTMR9 MTUS2 NMI RARG TRIM27	52 interactors: BLZF1 BRMS1L CARD9 CCHCR1 CDR2 CYTH4 DDIT3 DYNLL1 EIF4E2 FAM184A FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MPP1 MTMR6 MYO5B NDC80 NFIL3 PSMC3 RAD51D RALBP1 RASSF5 RNF20 RNF40 SH3RF2 SMARCE1 SP100 SPAG5 SPP1 THRA TMCC2 TRAF2 TRIM27 WDYHV1 ZBED1 ZGPAT
Entrez ID		9107	51421
HPRD ID		11946	16485
Ensembl ID		ENSG00000139505	ENSG00000114019
Uniprot IDs		Q9Y217	Q9Y2J4
PDB IDs		2YF0
Enriched GO Terms of Interacting Partners?		Growth Plate Cartilage Chondrocyte Growth Negative Regulation Of Interleukin-2 Secretion Growth Plate Cartilage Chondrocyte Development Harderian Gland Development Chondrocyte Hypertrophy Growth Plate Cartilage Chondrocyte Differentiation Negative Regulation Of Calcium Ion Import Wnt Signaling Pathway Retinal Pigment Epithelium Development Interferon-gamma Secretion Lacrimal Gland Development Regulation Of Cellular Component Size	Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Protein Localization Histone H2B Ubiquitination Regulation Of Cellular Localization Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Polyubiquitination Mitotic Cell Cycle Organelle Organization Chromosome Organization Protein Ubiquitination Histone Monoubiquitination Negative Regulation Of Viral Transcription Cell Cycle Negative Regulation Of Transcription, DNA-templated Protein Modification By Small Protein Conjugation Regulation Of Establishment Of Protein Localization Protein K63-linked Ubiquitination Histone Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter Protein Trimerization Negative Regulation Of Determination Of Dorsal Identity Regulation Of Metaphase Plate Congression Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Protein Metabolic Process Response To Organic Substance Cellular Response To Glucagon Stimulus
Tagcloud ?			actin alanine amots angiomotin collectively consensus contain core dissociation endogenously exogenous filaments hippo hxrxxs lats1 lats2 mapping mediate members mimic negatively phospho promoted s175a s175d serine taz yap
Tagcloud (Difference) ?			actin alanine amots angiomotin collectively consensus contain core dissociation endogenously exogenous filaments hippo hxrxxs lats1 lats2 mapping mediate members mimic negatively phospho promoted s175a s175d serine taz yap
Tagcloud (Intersection) ?