AMOTL2 and NFIL3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		AMOTL2	NFIL3
Gene Name		angiomotin like 2	nuclear factor, interleukin 3 regulated
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Tight Junction Apical Plasma Membrane Cytoplasmic Vesicle Recycling Endosome	Nucleus
	Molecular Function	Protein Binding Identical Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity
	Biological Process	Wnt Signaling Pathway Hippo Signaling	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Immune Response Circadian Rhythm Positive Regulation Of Gene Expression Cellular Response To Interleukin-4
Pathways		Signaling by Hippo
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		52 interactors: BLZF1 BRMS1L CARD9 CCHCR1 CDR2 CYTH4 DDIT3 DYNLL1 EIF4E2 FAM184A FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MPP1 MTMR6 MYO5B NDC80 NFIL3 PSMC3 RAD51D RALBP1 RASSF5 RNF20 RNF40 SH3RF2 SMARCE1 SP100 SPAG5 SPP1 THRA TMCC2 TRAF2 TRIM27 WDYHV1 ZBED1 ZGPAT	8 interactors: AMOTL2 BATF CREB3 DDIT3 DR1 MAFF MAFG TRAF2
Entrez ID		51421	4783
HPRD ID		16485	05619
Ensembl ID		ENSG00000114019	ENSG00000165030
Uniprot IDs		Q9Y2J4	Q16649
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Protein Localization Histone H2B Ubiquitination Regulation Of Cellular Localization Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Polyubiquitination Mitotic Cell Cycle Organelle Organization Chromosome Organization Protein Ubiquitination Histone Monoubiquitination Negative Regulation Of Viral Transcription Cell Cycle Negative Regulation Of Transcription, DNA-templated Protein Modification By Small Protein Conjugation Regulation Of Establishment Of Protein Localization Protein K63-linked Ubiquitination Histone Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter Protein Trimerization Negative Regulation Of Determination Of Dorsal Identity Regulation Of Metaphase Plate Congression Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Protein Metabolic Process Response To Organic Substance Cellular Response To Glucagon Stimulus	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Epidermal Cell Differentiation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Response To Stress Gene Expression Regulation Of Epidermis Development Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Determination Of Dorsal Identity Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Release From Viral Latency Regulation Of Transcription Involved In Anterior/posterior Axis Specification Response To Unfolded Protein Regulation Of Epithelial Cell Differentiation Cellular Response To Stress Nucleobase-containing Compound Metabolic Process Response To Endoplasmic Reticulum Stress Heterocycle Metabolic Process T-helper 2 Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Cellular Aromatic Compound Metabolic Process Biosynthetic Process T-helper 17 Cell Lineage Commitment Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Deacetylase Activity Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Signal Transduction T-helper 17 Cell Differentiation Negative Regulation Of Glial Cell Apoptotic Process Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Establishment Of Viral Latency ER Overload Response Response To Stimulus Positive Regulation Of Protein Homodimerization Activity Type 2 Immune Response Wnt Signaling Pathway
Tagcloud ?		actin alanine amots angiomotin collectively consensus contain core dissociation endogenously exogenous filaments hippo hxrxxs lats1 lats2 mapping mediate members mimic negatively phospho promoted s175a s175d serine taz yap	cardiomyoblast cardiomyocytes copyright correlates fibrosis h9c2 heart hearts hemorrhagic hypertrophy hypoxia hypoxic igf2 igf2r leucine luciferase mannose precipitation protected pull repress reserved rights stranded subjected superfamily suppresses triggers zipper
Tagcloud (Difference) ?		actin alanine amots angiomotin collectively consensus contain core dissociation endogenously exogenous filaments hippo hxrxxs lats1 lats2 mapping mediate members mimic negatively phospho promoted s175a s175d serine taz yap	cardiomyoblast cardiomyocytes copyright correlates fibrosis h9c2 heart hearts hemorrhagic hypertrophy hypoxia hypoxic igf2 igf2r leucine luciferase mannose precipitation protected pull repress reserved rights stranded subjected superfamily suppresses triggers zipper
Tagcloud (Intersection) ?