MTMR6 and MTMR9

Number of citations of the paper that reports this interaction (PMID 12890864)
22

Data Source:
BioGRID (two hybrid, pull down, affinity chromatography technology)
HPRD (in vitro, in vivo)

		MTMR6	MTMR9
Gene Name		myotubularin related protein 6	myotubularin related protein 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Cytoplasm Cytosol	Cytoplasm
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Calcium-activated Potassium Channel Activity	Protein Binding Phosphatase Activity Enzyme Regulator Activity
	Biological Process	Protein Dephosphorylation Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Peptidyl-tyrosine Dephosphorylation Small Molecule Metabolic Process Potassium Ion Transmembrane Transport	Dephosphorylation Regulation Of Catalytic Activity
Pathways		Synthesis of PIPs at the plasma membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS			Retinal vascular caliber ( 21060863)
Protein-Protein Interactions		6 interactors: AMOTL2 MTMR9 MTUS2 NMI RARG TRIM27	11 interactors: EMILIN1 EWSR1 KDM1A LNX1 MOS MTMR6 MTMR7 MTMR8 NMI SPG21 VAC14
Entrez ID		9107	66036
HPRD ID		11946	09377
Ensembl ID		ENSG00000139505	ENSG00000104643
Uniprot IDs		Q9Y217	Q96QG7
PDB IDs		2YF0
Enriched GO Terms of Interacting Partners?		Growth Plate Cartilage Chondrocyte Growth Negative Regulation Of Interleukin-2 Secretion Growth Plate Cartilage Chondrocyte Development Harderian Gland Development Chondrocyte Hypertrophy Growth Plate Cartilage Chondrocyte Differentiation Negative Regulation Of Calcium Ion Import Wnt Signaling Pathway Retinal Pigment Epithelium Development Interferon-gamma Secretion Lacrimal Gland Development Regulation Of Cellular Component Size	Phosphatidylinositol Biosynthetic Process Peptidyl-tyrosine Dephosphorylation Glycerophospholipid Biosynthetic Process Phosphatidylinositol Metabolic Process Phospholipid Biosynthetic Process Protein Dephosphorylation Glycerophospholipid Metabolic Process Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle Regulation Of Primitive Erythrocyte Differentiation Glycerolipid Metabolic Process Phospholipid Metabolic Process Dephosphorylation Cellular Protein Modification Process Negative Regulation Of Meiotic Cell Cycle Phase Transition Lipid Biosynthetic Process Establishment Of Meiotic Spindle Localization Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation
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