SLC7A7 and SLC3A2

Number of citations of the paper that reports this interaction (PMID 9829974)
32

Data Source:
HPRD (in vitro)

		SLC7A7	SLC3A2
Gene Name		solute carrier family 7 (amino acid transporter light chain, y+L system), member 7	solute carrier family 3 (amino acid transporter heavy chain), member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane	Nucleus Nucleoplasm Cytoplasm Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Apical Plasma Membrane Melanosome Extracellular Vesicular Exosome
	Molecular Function	Amino Acid Transmembrane Transporter Activity	Double-stranded RNA Binding Catalytic Activity Calcium:sodium Antiporter Activity Protein Binding Neutral Amino Acid Transmembrane Transporter Activity Cation Binding Poly(A) RNA Binding
	Biological Process	Amino Acid Transmembrane Transport Protein Complex Assembly Cellular Amino Acid Metabolic Process Transport Ion Transport Amino Acid Transport Blood Coagulation Leukocyte Migration Transmembrane Transport	Carbohydrate Metabolic Process Ion Transport Calcium Ion Transport Amino Acid Transport Blood Coagulation Tryptophan Transport Cell Growth Sodium Ion Transmembrane Transport Response To Exogenous DsRNA Leukocyte Migration Transmembrane Transport Leucine Import
Pathways		Transport of inorganic cations/anions and amino acids/oligopeptides Amino acid transport across the plasma membrane SLC-mediated transmembrane transport Basigin interactions Cell surface interactions at the vascular wall	Transport of inorganic cations/anions and amino acids/oligopeptides Amino acid transport across the plasma membrane SLC-mediated transmembrane transport Basigin interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: NEDD4L SLC3A2	11 interactors: EGFR FAM57A HNRNPD ICAM1 ITGB1 SLC7A10 SLC7A11 SLC7A5 SLC7A7 SLC7A8 VHL
Entrez ID		9056	6520
HPRD ID		04667	01148
Ensembl ID		ENSG00000155465	ENSG00000168003
Uniprot IDs		Q9UM01	J3KPF3 P08195
PDB IDs			2DH2 2DH3
Enriched GO Terms of Interacting Partners?		Leucine Import Sodium Ion Transport Tryptophan Transport Positive Regulation Of Caveolin-mediated Endocytosis Aromatic Amino Acid Transport Leucine Transport Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Protein Localization To Cell Surface Regulation Of Tight Junction Assembly Branched-chain Amino Acid Transport Monovalent Inorganic Cation Transport Negative Regulation Of Sodium Ion Transport Negative Regulation Of Potassium Ion Transmembrane Transport Cellular Sodium Ion Homeostasis Amino Acid Import Metal Ion Transport Ventricular Cardiac Muscle Cell Action Potential Regulation Of Protein Localization To Cell Surface Negative Regulation Of Potassium Ion Transport Negative Regulation Of Systemic Arterial Blood Pressure Regulation Of Membrane Repolarization Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Sodium Ion Homeostasis Regulation Of Potassium Ion Transmembrane Transporter Activity Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Sodium Ion Transmembrane Transporter Activity Cation Transport Positive Regulation Of Cation Channel Activity Positive Regulation Of Sodium Ion Transport Cardiac Muscle Cell Action Potential Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Membrane Depolarization Regulation Of Sodium Ion Transmembrane Transport Response To Salt Stress Ion Transmembrane Transport Protein K48-linked Ubiquitination Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Transporter Activity Protein Monoubiquitination Regulation Of Cardiac Muscle Cell Contraction Neutral Amino Acid Transport Excretion Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Blood Pressure Positive Regulation Of Ion Transmembrane Transporter Activity Response To Exogenous DsRNA Negative Regulation Of Transmembrane Transport	Leukocyte Migration Cell Migration Cell Motility Amino Acid Transmembrane Transport Amino Acid Transport Locomotion Neutral Amino Acid Transport Blood Coagulation Hemostasis L-alpha-amino Acid Transmembrane Transport Movement Of Cell Or Subcellular Component Regulation Of Body Fluid Levels Wound Healing Carboxylic Acid Transport Organic Acid Transport Response To Wounding Immune System Process Response To Stress Anion Transmembrane Transport Organic Anion Transport Anion Transport Cell Adhesion Mediated By Integrin Single Organismal Cell-cell Adhesion Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Vasoconstriction Ion Transmembrane Transport Response To Gonadotropin Cell Activation Viral Entry Into Host Cell Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Entry Into Host Cell Rhythmic Process Regulation Of Vasoconstriction Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Cell Migration Chemical Homeostasis Positive Regulation Of Cell Motility Response To Organic Cyclic Compound Positive Regulation Of Cellular Component Movement Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Mechanical Stimulus Positive Regulation Of Locomotion Negative Regulation Of Apoptotic Process Transmembrane Transport Negative Regulation Of Programmed Cell Death Ion Transport Alkanesulfonate Metabolic Process Response To Sulfur Dioxide D-alanine Transport
Tagcloud ?		aif1 aracne attempt bioinformatics blnk ccnd2 complexity comprising connected connections csgalnact1 fam53b kif21b neighbor neighbors networks panel playing publicly reconstructed reconstruction reproducible robust sets shared signatures technologies tmpo whsc1	adenocarcinoma anchorage approved braf cd74 consisting constitutively driver druggable erbb4 exclusively ezr fusion fusions her3 ima imas kiaa1468 kras mucinous mutually nih3t3 nrg1 oncogenic ret sequencing transcriptome trim24 tumorigenicity
Tagcloud (Difference) ?		aif1 aracne attempt bioinformatics blnk ccnd2 complexity comprising connected connections csgalnact1 fam53b kif21b neighbor neighbors networks panel playing publicly reconstructed reconstruction reproducible robust sets shared signatures technologies tmpo whsc1	adenocarcinoma anchorage approved braf cd74 consisting constitutively driver druggable erbb4 exclusively ezr fusion fusions her3 ima imas kiaa1468 kras mucinous mutually nih3t3 nrg1 oncogenic ret sequencing transcriptome trim24 tumorigenicity
Tagcloud (Intersection) ?