CHMP1B and CHMP4B

Number of citations of the paper that reports this interaction (PMID 16730941)
46

Data Source:
HPRD (two hybrid)

		CHMP1B	CHMP4B
Gene Name		charged multivesicular body protein 1B	charged multivesicular body protein 4B
Image
Gene Ontology Annotations	Cellular Component	Cytosol Late Endosome Membrane Extracellular Vesicular Exosome	ESCRT III Complex Nucleus Cytoplasm Endosome Cytosol Cytoplasmic Side Of Plasma Membrane Midbody Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Cytokinesis Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Establishment Of Protein Localization Regulation Of Mitotic Spindle Assembly	Cell Separation After Cytokinesis Posttranslational Protein Targeting To Membrane Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Viral Process Endosomal Transport Viral Life Cycle Maintenance Of Lens Transparency Viral Budding Via Host ESCRT Complex Viral Budding Regulation Of Viral Process Protein Homooligomerization Negative Regulation Of Cell Death Membrane Organization Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Neuron Death Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Autophagic Vacuole Assembly
Pathways			HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS			Stearic acid (18:0) plasma levels ( 23362303)
Protein-Protein Interactions		16 interactors: CHMP1A CHMP4B CHMP5 CNOT10 KNSTRN RAB11A RASSF7 SNRNP200 SPAST SSRP1 STAMBP SUCLG1 USP54 USP8 VPS4A VPS4B	14 interactors: CHMP1B CHMP3 CHMP4A CHMP4C CHMP5 CHMP6 EXOSC9 HIPK2 PDCD6IP PIAS2 PTPN23 STAMBP UBE2I VPS4A
Entrez ID		57132	128866
HPRD ID		12106	16642
Ensembl ID		ENSG00000255112	ENSG00000101421
Uniprot IDs		Q7LBR1	Q9H444
PDB IDs		3EAB	3C3Q 3UM3 4ABM
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Cell Division Mitotic Sister Chromatid Segregation Metaphase Plate Congression Sister Chromatid Segregation Establishment Of Chromosome Localization Mitotic Cell Cycle Process Mitotic Cell Cycle Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Cytokinesis Chromosome Segregation Regulation Of Mitotic Spindle Organization Cell Cycle Process Regulation Of Microtubule Cytoskeleton Organization Mitotic Nuclear Division Regulation Of Microtubule-based Process Cell Cycle Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding Via Host ESCRT Complex Nucleus Organization Regulation Of Centrosome Duplication Viral Budding Regulation Of Centrosome Cycle Establishment Of Organelle Localization Chromosome Organization Organelle Localization Endosomal Transport Virion Assembly Regulation Of Cell Cycle Process Regulation Of Cell Division Regulation Of Cytoskeleton Organization Endosome Organization Regulation Of Mitotic Nuclear Division Mitotic Cytokinesis Regulation Of Mitotic Cell Cycle Organelle Organization Viral Life Cycle Positive Regulation Of Viral Release From Host Cell Cellular Macromolecule Catabolic Process Positive Regulation Of Viral Process Regulation Of Organelle Organization Vacuolar Transport Regulation Of Cell Cycle Membrane Budding Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion	Cell Separation After Cytokinesis Cell Division Mitotic Metaphase Plate Congression Metaphase Plate Congression Establishment Of Chromosome Localization Nucleus Organization Vacuolar Transport Mitotic Sister Chromatid Segregation Viral Process Sister Chromatid Segregation Viral Life Cycle Chromosome Segregation Regulation Of Centrosome Duplication Regulation Of Centrosome Cycle Mitotic Nuclear Division Mitotic Cell Cycle Process Endosomal Transport Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Mitotic Cell Cycle Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Protein Transport Viral Budding Regulation Of Microtubule Cytoskeleton Organization Establishment Of Organelle Localization Regulation Of Spindle Assembly Establishment Of Protein Localization Cell Cycle Process Regulation Of Microtubule-based Process Regulation Of Mitotic Spindle Organization Organelle Localization Regulation Of Cell Cycle Process Protein Localization Membrane Organization Cell Cycle Virion Assembly Regulation Of Cell Cycle Regulation Of Cellular Component Organization Abscission Cellular Macromolecule Catabolic Process Regulation Of Cytoskeleton Organization Regulation Of Organelle Organization Positive Regulation Of Viral Release From Host Cell Intracellular Transport Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Cell Division Cellular Protein Catabolic Process Negative Regulation Of Cytokinesis Membrane Budding Organelle Organization
Tagcloud ?		aux1 auxin disorganized endosomal escrt gradients internalized lip5 lumenal meristems mislocalized multivesicular mvb mvbs pin1 pin2 pinformed1 protein1a resistant1 rudimentary seedling seedlings skd1 sorted stomata symmetry thaliana vacuolar	aculeiform adcc arg58his beaded bfsp1 bfsp2 cataract cerulean connexins coralliform cryaa cryba2 cryba4 crybb1 crybb3 cryga crygb crygc crygd crygs crystallins fasciculiform flaky gja3 gja8 lim2 macedonia pro23thr tmem114
Tagcloud (Difference) ?		aux1 auxin disorganized endosomal escrt gradients internalized lip5 lumenal meristems mislocalized multivesicular mvb mvbs pin1 pin2 pinformed1 protein1a resistant1 rudimentary seedling seedlings skd1 sorted stomata symmetry thaliana vacuolar	aculeiform adcc arg58his beaded bfsp1 bfsp2 cataract cerulean connexins coralliform cryaa cryba2 cryba4 crybb1 crybb3 cryga crygb crygc crygd crygs crystallins fasciculiform flaky gja3 gja8 lim2 macedonia pro23thr tmem114
Tagcloud (Intersection) ?