CD209 and CEACAM1

Number of citations of the paper that reports this interaction (PMID 16246332)
17

Data Source:
HPRD (in vivo)

		CD209	CEACAM1
Gene Name		CD209 molecule	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Mannose Binding Carbohydrate Binding Peptide Antigen Binding Virion Binding Metal Ion Binding	Molecular_function Protein Binding Protein Homodimerization Activity
	Biological Process	Endocytosis Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-cell Recognition Modulation By Virus Of Host Morphology Or Physiology Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Regulation Of T Cell Proliferation Innate Immune Response Peptide Antigen Transport Intracellular Transport Of Virus	Angiogenesis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Integrin-mediated Signaling Pathway Blood Coagulation Cell Migration Leukocyte Migration
Pathways			Fibronectin matrix formation Cell surface interactions at the vascular wall
Drugs			Arcitumomab Alpha-D-Mannose
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CEACAM1 CLEC4M CLU ICAM2 ICAM3 ITGAM VAC14	18 interactors: ADRB2 ANXA2 CARTPT CD209 CEACAM3 CEACAM5 CEACAM6 CEACAM7 CEACAM8 EGFR FLNA INSR MAP3K10 PTPN11 PTPN6 PXN SHC1 SRC
Entrez ID		30835	634
HPRD ID		05241	00191
Ensembl ID		ENSG00000090659	ENSG00000079385
Uniprot IDs		B2R907 B4E2A8 M0QZG5 M0R0P0 Q9NNX6	P13688 Q3KRG8
PDB IDs		1K9I 1SL4 1SL5 2B6B 2IT5 2IT6 2XR5 2XR6	2GK2
Enriched GO Terms of Interacting Partners?		Cell Adhesion Single Organismal Cell-cell Adhesion Regulation Of Immune Response Extracellular Matrix Organization Extracellular Structure Organization Blood Coagulation Hemostasis Regulation Of Immune System Process Positive Regulation Of Tau-protein Kinase Activity Microglial Cell Proliferation Regulation Of Neuronal Signal Transduction Glial Cell Development Regulation Of Body Fluid Levels Wound Healing Leukocyte Proliferation Integrin-mediated Signaling Pathway Microglia Development Positive Regulation Of Neurofibrillary Tangle Assembly Response To Wounding Peptide Antigen Transport Central Nervous System Myelin Maintenance Glial Cell Differentiation Innate Immune Response Regulation Of Tau-protein Kinase Activity Negative Regulation Of Protein Homooligomerization Ectodermal Cell Differentiation Leukocyte Migration Immune System Process Positive Regulation Of Inclusion Body Assembly Regulation Of Beta-amyloid Clearance Gliogenesis Virion Attachment To Host Cell Positive Regulation Of Beta-amyloid Formation Negative Regulation Of Protein Oligomerization Adhesion Of Symbiont To Host Negative Regulation Of Beta-amyloid Formation Leukocyte Cell-cell Adhesion Chaperone-mediated Protein Complex Assembly Microglial Cell Activation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Glial Cell Proliferation Response To Misfolded Protein Immune Response Regulation Of Beta-amyloid Formation Leukocyte Migration Involved In Inflammatory Response Defense Response Regulation Of Inclusion Body Assembly Reverse Cholesterol Transport Regulation Of Amyloid Precursor Protein Catabolic Process Central Nervous System Myelination	Activation Of Protein Kinase Activity Positive Regulation Of Intracellular Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of MAP Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Transferase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Signal Transduction Positive Regulation Of Protein Modification Process Regulation Of Phosphorylation Positive Regulation Of MAP Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Body Fluid Levels Regulation Of Cellular Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Stress Leukocyte Migration Blood Coagulation Hemostasis Cellular Response To Organonitrogen Compound Peptidyl-tyrosine Phosphorylation Single Organismal Cell-cell Adhesion Regulation Of Catalytic Activity Activation Of MAPK Activity Cellular Response To Peptide Hormone Stimulus Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Peptide Cellular Response To Hormone Stimulus Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Wound Healing Regulation Of Signal Transduction Positive Regulation Of Catalytic Activity Response To Wounding Positive Regulation Of Transport Response To Peptide Hormone Cell Adhesion Regulation Of Signaling Abortive Mitotic Cell Cycle
Tagcloud ?		accreta assure basalis cd205 cd25 cd56 cd68 cd83 cytokeratin dec205 decidua evt extravillous foxp3 immature increta infertility intrauterine iug mann maturated miscarriage originates parietalis preeclampsia treg trophoblast whitney	4l adhesion carcinoembryonic chemotactic clinicopathologic cxcl density explore extent immunohistochemistry infiltration ln lymph metastasis microarray neutrophil neutrophils node overexpression peritumoral poorer probe qrt squamous tissues tongue tscc upregulate upregulating
Tagcloud (Difference) ?		accreta assure basalis cd205 cd25 cd56 cd68 cd83 cytokeratin dec205 decidua evt extravillous foxp3 immature increta infertility intrauterine iug mann maturated miscarriage originates parietalis preeclampsia treg trophoblast whitney	4l adhesion carcinoembryonic chemotactic clinicopathologic cxcl density explore extent immunohistochemistry infiltration ln lymph metastasis microarray neutrophil neutrophils node overexpression peritumoral poorer probe qrt squamous tissues tongue tscc upregulate upregulating
Tagcloud (Intersection) ?