CD209 and ICAM2

Number of citations of the paper that reports this interaction (PubMedID 11017109)
0

Data Source:
HPRD (in vitro)

		CD209	ICAM2
Description		CD209 molecule	intercellular adhesion molecule 2
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Host Cell	Uropod Plasma Membrane Microvillus Membrane Cleavage Furrow Cell Projection Cell Periphery
	Molecular Function	Virus Receptor Activity Protein Binding D-mannose Binding Carbohydrate Binding Pattern Recognition Receptor Activity Peptide Antigen Binding Virion Binding Metal Ion Binding	Integrin Binding
	Biological Process	Adaptive Immune Response Immune System Process Endocytosis Immune Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-cell Recognition Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Positive Regulation Of T Cell Proliferation Regulation Of T Cell Proliferation Innate Immune Response Symbiont Entry Into Host Cell Peptide Antigen Transport Intracellular Transport Of Virus B Cell Adhesion Positive Regulation Of Viral Life Cycle	Cell Adhesion Cell-cell Adhesion
Pathways		CD209 (DC-SIGN) signaling Butyrophilin (BTN) family interactions RSV-host interactions	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions CD209 (DC-SIGN) signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)
Interacting Genes		10 interacting genes: CEACAM1 CLEC4M CLU CRYAA ICAM2 ICAM3 IFT20 ITGAM TCEAL8 VAC14	8 interacting genes: ATP13A2 CD209 EZR F2RL1 ITGAM ITGB2 MSN RDX
Entrez ID		30835	3384
HPRD ID		05241	00888
Ensembl ID		ENSG00000090659	ENSG00000108622
Uniprot IDs		B2R907 B4E2A8 M0R0P0 Q9NNX6 X6RB12	P13598 Q6FHE2
PDB IDs		1K9I 1SL4 1SL5 2B6B 2IT5 2IT6 2XR5 2XR6 6GHV 7NL6 7NL7 9EMQ 9EMR 9EMS	1ZXQ
Enriched GO Terms of Interacting Partners?		Cell-cell Adhesion Endocytosis Cell Adhesion Amyloid-beta Clearance Integrin Binding Receptor-mediated Endocytosis Microglial Cell Activation Regulation Of Vesicle-mediated Transport Leukocyte Activation Involved In Inflammatory Response Import Into Cell Signaling Receptor Activity Macrophage Activation Perinuclear Endoplasmic Reticulum Lumen Regulation Of Neuronal Signal Transduction PAS Complex Tertiary Granule Membrane Microvillus Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Insulin Receptor Internalization Negative Regulation Of Cytotoxic T Cell Degranulation Negative Regulation Of Hepatocyte Proliferation Regulation Of Transport Regulation Of Leukocyte Mediated Cytotoxicity Specific Granule Membrane Integrin-mediated Signaling Pathway Cell Periphery Amyloid-beta Binding Negative Regulation Of Activation Of Membrane Attack Complex Positive Regulation Of Neurofibrillary Tangle Assembly Central Nervous System Myelin Maintenance Immune Complex Clearance Integrin AlphaM-beta2 Complex Positive Regulation Of Neutrophil Degranulation Response To Curcumin Vertebrate Eye-specific Patterning ICAM-3 Receptor Activity Peptide Antigen Transport Kinociliary Basal Body Opsin Transport Intraciliary Transport Particle Unfolded Protein Binding Insulin Catabolic Process Regulation Of Regulated Secretory Pathway Regulation Of Receptor-mediated Endocytosis Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy Chromaffin Granule Negative Regulation Of Dopamine Metabolic Process Positive Regulation Of Microglial Cell Mediated Cytotoxicity Complement-mediated Synapse Pruning Opsin Binding	Regulation Of Vesicle-mediated Transport Establishment Of Endothelial Barrier Endothelial Cell Development Regulation Of Protein Localization Positive Regulation Of Transport Leukocyte Cell-cell Adhesion Positive Regulation Of Early Endosome To Late Endosome Transport Positive Regulation Of Protein Localization To Early Endosome Positive Regulation Of Protein Localization To Endosome Regulation Of Cellular Localization Positive Regulation Of Exocytosis Regulation Of Cellular Component Size Cell Adhesion Molecule Binding Regulation Of Early Endosome To Late Endosome Transport Positive Regulation Of Superoxide Anion Generation Regulation Of Superoxide Anion Generation Integrin AlphaM-beta2 Complex Epithelial Cell Development Regulation Of Superoxide Metabolic Process Regulation Of Cell Shape Regulation Of Transport Plasma Membrane Raft Positive Regulation Of Protein Localization Positive Regulation Of Neutrophil Degranulation Regulation Of Exocytosis Cell-cell Adhesion Positive Regulation Of Regulated Secretory Pathway Negative Regulation Of Dopamine Metabolic Process Negative Regulation Of Catecholamine Metabolic Process Membrane To Membrane Docking Regulation Of Cell Morphogenesis Positive Regulation Of Reactive Oxygen Species Metabolic Process Microvillus Cytoskeletal Protein Binding Regulation Of Neutrophil Degranulation Regulation Of Intracellular Transport Microvillus Assembly Microvillus Organization Filopodium Positive Regulation Of Secretion By Cell Apical Part Of Cell Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Cell Periphery Complement Component C3b Binding Protein Kinase A Signaling Regulation Of Protein Catabolic Process Regulation Of Immune System Process Uropod Cell Adhesion
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