IFT20 and MED4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		IFT20	MED4
Gene Name		intraflagellar transport 20	mediator complex subunit 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Photoreceptor Outer Segment Golgi Apparatus Centrosome Centriole Cilium Microtubule Cytoskeleton Intraciliary Transport Particle B Motile Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Dendrite Terminus Extracellular Vesicular Exosome Primary Cilium Ciliary Tip Ciliary Base	Nucleus Nucleoplasm Membrane Mediator Complex
	Molecular Function	Opsin Binding Protein Binding	RNA Polymerase II Transcription Cofactor Activity Transcription Cofactor Activity Receptor Activity Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process	Kidney Development Organelle Organization Smoothened Signaling Pathway Visual Learning Protein Localization To Golgi Apparatus Photoreceptor Cell Outer Segment Organization Opsin Transport Intraciliary Transport Cilium Assembly Centrosome Localization Cardiac Muscle Cell Differentiation Regulation Of Canonical Wnt Signaling Pathway Neural Precursor Cell Proliferation Protein Localization To Cilium Regulation Of Cilium Assembly Regulation Of Autophagic Vacuole Assembly	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression Intracellular Steroid Hormone Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated
Pathways		Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport	PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: ABI2 BLOC1S6 CCDC53 CCDC67 CROCCP2 DISC1 DTNBP1 EMILIN1 EXOC7 FBF1 FSD2 GOLGA2 HAUS1 HTT IFT57 KIF3B KPNA2 KRT13 KXD1 MED4 NDC80 NUP54 NUP62 PSMA1 PTPN12 TREX1 USHBP1 WASF1 ZDHHC17	36 interactors: AES AMOT AP2M1 ATF7IP C1orf216 CCDC101 CCDC146 CCHCR1 CTDP1 CTNNBL1 FAM13C FOXJ3 FRMD6 FTCD HAUS1 IFT20 KIFC3 LRRFIP1 MAB21L3 MCRS1 MED13 MED25 MED30 MED9 NDC80 NDE1 PCBD2 PUM2 SDCBP SMARCD1 SMARCE1 SSX3 TNFAIP8 TXLNA USHBP1 WDTC1
Entrez ID		90410	29079
HPRD ID		17137	16145
Ensembl ID		ENSG00000109083	ENSG00000136146
Uniprot IDs		Q8IY31	Q9NPJ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Microtubule-based Process Cytoskeleton Organization Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Mitotic Cell Cycle Anterograde Axon Cargo Transport Mitotic Cell Cycle Process Microtubule Cytoskeleton Organization Microtubule-based Movement Establishment Of Organelle Localization Cellular Localization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Membrane Organization Establishment Of Localization In Cell Positive Regulation Of Actin Nucleation Establishment Of Vesicle Localization Cell Cycle Vesicle Localization Organelle Localization Cell Cycle Process Organelle Assembly Protein Localization Movement Of Cell Or Subcellular Component Centrosome Organization Intracellular Transport Nucleocytoplasmic Transport Anterograde Synaptic Vesicle Transport Nuclear Transport Rac Protein Signal Transduction Microtubule Organizing Center Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Establishment Of Cell Polarity Melanosome Organization Pigment Granule Organization Regulation Of Actin Nucleation Spindle Organization Protein Transport Vesicle Transport Along Microtubule Mitotic Nuclear Envelope Disassembly Establishment Of Protein Localization Cytoplasmic Transport Establishment Of Mitotic Spindle Orientation Nuclear Envelope Disassembly Establishment Or Maintenance Of Cell Polarity Mitotic Spindle Organization Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Neural Plate Formation	Organelle Organization Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Process Regulation Of Nitrogen Compound Metabolic Process Gene Expression Nucleosome Disassembly Cellular Protein Localization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Establishment Of Cell Polarity Cellular Localization Cellular Nitrogen Compound Metabolic Process Mitotic Nuclear Division Centrosome Localization Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Establishment Of Mitotic Spindle Orientation Androgen Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Mediator Complex Assembly Opsin Transport Regulation Of Cellular Process Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Nitrogen Compound Metabolic Process Chromosome Organization Establishment Or Maintenance Of Cell Polarity Chromatin Organization Cell Division Protein Localization Negative Regulation Of Transcription, DNA-templated Movement Of Cell Or Subcellular Component Spindle Localization Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Microtubule-based Process Pteridine-containing Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cytoskeleton Organization Negative Regulation Of RNA Biosynthetic Process
Tagcloud ?		anchors apparatus assembled caenorhabditis centrosomal chlamydomonas cilia cilium displaces dyf elipsa flag gmap210 golgi hspb11 ift172 ift25 ift54 ift54s ift88 immunoprecipitate intraflagellar liss localize motil orthologue orthologues traf3ip1
Tagcloud (Difference) ?		anchors apparatus assembled caenorhabditis centrosomal chlamydomonas cilia cilium displaces dyf elipsa flag gmap210 golgi hspb11 ift172 ift25 ift54 ift54s ift88 immunoprecipitate intraflagellar liss localize motil orthologue orthologues traf3ip1
Tagcloud (Intersection) ?