MED4 and TXLNA

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MED4	TXLNA
Gene Name		mediator complex subunit 4	taxilin alpha
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Mediator Complex	Extracellular Region Cytoplasm Membrane
	Molecular Function	RNA Polymerase II Transcription Cofactor Activity Transcription Cofactor Activity Receptor Activity Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding	Cytokine Activity Protein Binding Syntaxin Binding High Molecular Weight B Cell Growth Factor Receptor Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression Intracellular Steroid Hormone Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated	Exocytosis Cell Proliferation B Cell Activation
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		36 interactors: AES AMOT AP2M1 ATF7IP C1orf216 CCDC101 CCDC146 CCHCR1 CTDP1 CTNNBL1 FAM13C FOXJ3 FRMD6 FTCD HAUS1 IFT20 KIFC3 LRRFIP1 MAB21L3 MCRS1 MED13 MED25 MED30 MED9 NDC80 NDE1 PCBD2 PUM2 SDCBP SMARCD1 SMARCE1 SSX3 TNFAIP8 TXLNA USHBP1 WDTC1	53 interactors: AZI2 BRCA1 BTF3 BTF3L4 CCDC136 CCDC53 CCDC67 CCHCR1 CDR2 CEP44 CEP57L1 CEP63 DTNB EIF4ENIF1 GOLGA2 GORASP2 HAUS3 HYPK IKBKG KANK2 KRT13 KRT15 KRT20 KRT31 KRT38 KRT40 LCA5 MBIP MED4 MEOX1 MEOX2 NACA NDC80 NMI NSMCE2 NUP62 PPFIA1 RCOR3 RINT1 SMARCE1 SPERT STMN2 STX1A STX3 STX4 TBK1 TCL1A TFIP11 TNIP1 TP53BP2 TXLNB USHBP1 VPS52
Entrez ID		29079	200081
HPRD ID		16145	09408
Ensembl ID		ENSG00000136146	ENSG00000084652
Uniprot IDs		Q9NPJ6	P40222
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Process Regulation Of Nitrogen Compound Metabolic Process Gene Expression Nucleosome Disassembly Cellular Protein Localization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Establishment Of Cell Polarity Cellular Localization Cellular Nitrogen Compound Metabolic Process Mitotic Nuclear Division Centrosome Localization Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Establishment Of Mitotic Spindle Orientation Androgen Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Mediator Complex Assembly Opsin Transport Regulation Of Cellular Process Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Nitrogen Compound Metabolic Process Chromosome Organization Establishment Or Maintenance Of Cell Polarity Chromatin Organization Cell Division Protein Localization Negative Regulation Of Transcription, DNA-templated Movement Of Cell Or Subcellular Component Spindle Localization Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Microtubule-based Process Pteridine-containing Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cytoskeleton Organization Negative Regulation Of RNA Biosynthetic Process	Synaptic Vesicle Fusion To Presynaptic Membrane Dendritic Cell Proliferation Organelle Organization Protein Localization Cell Cycle Protein Transport Establishment Of Protein Localization Mitotic Cell Cycle Neurotransmitter Secretion Somite Specification Positive Regulation Of Protein Localization To Cell Surface Regulation Of Neurotransmitter Levels Vesicle Fusion Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Exocytosis I-kappaB Kinase/NF-kappaB Signaling Neurotransmitter Transport Establishment Of Organelle Localization Microtubule-based Process Type I Interferon Production Developmental Process Organelle Fusion Centriole Assembly Positive Regulation Of Transcription, DNA-templated Vesicle Docking Establishment Of Vesicle Localization Establishment Of Localization In Cell Segment Specification Interferon-gamma Production Vesicle Localization Cellular Localization Centrosome Organization Membrane Docking Regulation Of Protein Localization To Cell Surface Regulation Of I-kappaB Kinase/NF-kappaB Signaling Organelle Localization Microtubule Cytoskeleton Organization Microtubule Organizing Center Organization Glutamate Secretion Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Toll-like Receptor Signaling Pathway Synaptic Vesicle Transport Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Synaptic Transmission Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Spindle Organization Membrane Fusion Pattern Recognition Receptor Signaling Pathway
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