CCNG2 and EFHC2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		CCNG2	EFHC2
Description		cyclin G2	EF-hand domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Cytoplasm	Cytoplasm Cytoskeleton Microtubule Axonemal Microtubule Cilium Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity	Calcium Ion Binding Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Cell Division Regulation Of Cell Cycle	Regulation Of Neuron Projection Development Flagellated Sperm Motility Cellular Response To Leukemia Inhibitory Factor
Pathways		FOXO-mediated transcription of cell cycle genes
Drugs
Diseases
GWAS		Hormone measurements ( 30576415)	Body mass index and diastolic blood pressure (bivariate analysis) ( 33539483) Glaucoma (primary open-angle) ( 33627673) Mean arterial pressure ( 29403010)
Interacting Genes		7 interacting genes: EFHC2 NRIP2 PPP2CA PTPA TASOR2 TCF7L2 ZNF410	100 interacting genes: - AASDHPPT ARHGEF5 ARMC7 ATOSB CABP2 CACNB4 CARD9 CCDC102B CCDC120 CCDC13 CCDC57 CCHCR1 CCNG2 CDKN2A CLIC3 COPE CPNE2 CPNE7 CYFIP1 DCLK1 DDX6 DGCR6 DRC7 EDC3 EFHC1 EGLN3 EMD ENKD1 ESRRG EXOC8 EXOSC5 FAM107A FAM124B FAM221B FBXL19 GEM GLYCTK GOLGA1 GPKOW GRB2 GYS1 HDAC4 HGS HNRNPLL INPP5J JAKMIP2 KANK2 KCTD7 KIF9 L3MBTL2 LMNB2 LMO2 LNX1 LONRF1 MAGOHB MAPK9 MID2 MISP MTCL2 MYLIP MYO5B NCDN NCK2 NDOR1 NEK6 NFKBID NME7 NR3C1 PBLD PHF1 PIBF1 PICK1 PLOD3 POLR1C PRPF18 PTK6 QARS1 RAD51D RCOR3 RECK RHOBTB3 RUNX1T1 SNRNP25 SPATA18 SPG21 STK16 TBC1D1 TBC1D22B TEKT4 TRIM42 TRIM50 TSSK3 TUBGCP4 TXK U2AF1 USP2 ZBTB16 ZFHX3 ZZZ3
Entrez ID		901	80258
HPRD ID		04438	06540
Ensembl ID		ENSG00000138764	ENSG00000183690
Uniprot IDs		Q16589	Q5JST6
PDB IDs			2Z13 2Z14 7UNG 8J07
Enriched GO Terms of Interacting Partners?		Protein Phosphatase Type 2A Complex Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Small Molecule Metabolic Process RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Negative Regulation Of Metabolic Process RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity Phosphoprotein Phosphatase Activity Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress Negative Regulation Of Wnt Signaling Pathway Regulation Of Epithelial To Mesenchymal Transition Protein Tyrosine Phosphatase Activator Activity Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Beta-catenin-TCF7L2 Complex Catenin-TCF7L2 Complex Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Proteoglycan Biosynthetic Process Myoblast Fate Commitment Phosphatase Activator Activity Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Maintenance Of DNA Repeat Elements Armadillo Repeat Domain Binding Protein Serine/threonine Phosphatase Complex Peptidyl-threonine Dephosphorylation	Cytoplasm Protein Binding Protein Phosphorylation Cytoskeleton Regulation Of Podosome Assembly Phosphorylation Centrosome
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