TIMM17A and TIMM44

Number of citations of the paper that reports this interaction (PMID 10393182)
18

Data Source:
HPRD (in vitro)

		TIMM17A	TIMM44
Gene Name		translocase of inner mitochondrial membrane 17 homolog A (yeast)	translocase of inner mitochondrial membrane 44 homolog (yeast)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Inner Membrane Presequence Translocase Complex Integral Component Of Mitochondrial Inner Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity	Protein Binding ATP Binding P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity Chaperone Binding
	Biological Process	Protein Targeting To Mitochondrion Cellular Protein Metabolic Process Protein Transmembrane Transport	Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Matrix Cellular Protein Metabolic Process
Pathways		Mitochondrial protein import	Mitochondrial protein import
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: HAP1 TIMM44 TUBA1A	5 interactors: ARAF CMTM5 HSPA4 PRPF6 TIMM17A
Entrez ID		10440	10469
HPRD ID		05449	05450
Ensembl ID		ENSG00000134375	ENSG00000104980
Uniprot IDs		Q99595	O43615
PDB IDs			2CW9
Enriched GO Terms of Interacting Partners?		Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Intracellular Transport Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Cilium Assembly Establishment Of Localization In Cell Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Cellular Localization Hypothalamus Cell Differentiation Negative Regulation Of Beta-amyloid Formation Protein Import Into Mitochondrial Matrix Retrograde Axon Cargo Transport Negative Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Microtubule-based Movement Positive Regulation Of Synaptic Transmission, GABAergic Nucleotide-excision Repair, DNA Gap Filling Negative Regulation Of Smooth Muscle Cell Migration DNA Demethylation Organelle Organization Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Telomere Maintenance Via Semi-conservative Replication Regulation Of Beta-amyloid Formation Regulation Of Cilium Assembly Nuclear DNA Replication Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Amyloid Precursor Protein Catabolic Process Telomere Maintenance Via Recombination Mitotic Cell Cycle Positive Regulation Of ERBB Signaling Pathway Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Microtubule-based Process Hypothalamus Development Positive Regulation Of Organelle Assembly Positive Regulation Of Cell Cycle G1/S Phase Transition Anterograde Axon Cargo Transport Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Cation Channel Activity DNA Catabolic Process, Exonucleolytic Vesicle Transport Along Microtubule Regulation Of Synaptic Transmission, GABAergic Positive Regulation Of DNA Repair Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Receptor Activity Cellular Response To Interleukin-4 Regulation Of Smooth Muscle Cell Migration	Protein Transmembrane Transport Protein Targeting To Mitochondrion Protein Localization To Mitochondrion Mitochondrial Transport Protein Import Into Mitochondrial Outer Membrane Establishment Of Protein Localization To Organelle Mitochondrion Organization Chaperone-mediated Protein Complex Assembly Spliceosomal Tri-snRNP Complex Assembly Protein Targeting Protein Localization To Organelle Negative Regulation Of Myoblast Differentiation
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