PTPA and KISS1R

Number of citations of the paper that reports this interaction (PubMedID 18977201)
0

Data Source:
BioGRID (pull down)

		PTPA	KISS1R
Description		protein phosphatase 2 phosphatase activator	KISS1 receptor
Image
GO Annotations	Cellular Component	Protein Phosphatase Type 2A Complex Nucleus Nucleoplasm Cytoplasm Calcium Channel Complex Extracellular Exosome ATPase Complex	Plasma Membrane Cilium Cell Surface Membrane
	Molecular Function	Nucleotide Binding Peptidyl-prolyl Cis-trans Isomerase Activity Phosphoprotein Phosphatase Activity Signaling Receptor Binding Protein Binding ATP Binding Protein Tyrosine Phosphatase Activator Activity Isomerase Activity Phosphatase Activator Activity Protein Phosphatase Regulator Activity Phosphatase Binding Protein Homodimerization Activity Metal Ion Binding Protein Phosphatase 2A Binding	G Protein-coupled Receptor Activity Protein Binding Neuropeptide Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Mitotic Spindle Organization Positive Regulation Of Apoptotic Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Positive Regulation Of Hormone Secretion
Pathways			Peptide ligand-binding receptors G alpha (q) signalling events
Drugs			ANZ-100
Diseases			Hypogonadotropic hypogonadism; Kallmann syndrome (KAL) Precocious puberty, including: Central precocious puberty (CEPREPU); Familial male precocious puberty (FMPP)
GWAS			Menopause (age at onset) ( 26414677) Sweet taste preference ( 32572145)
Interacting Genes		32 interacting genes: AKT1 AMOT APP AURKB CCDC125 CCNE1 CCNG1 CCNG2 CSNK2A1 CYLD DTD1 EIF4EBP1 F3 FOXO3 GRIN3A GSK3B H2AX HDAC4 KISS1R MAPT MID1 NIF3L1 PPP2R1A PPP2R3A PRKCB RACGAP1 SGO1 SPG21 SRC SULT4A1 TEP1 TERT	3 interacting genes: KISS1 PPP2CA PTPA
Entrez ID		5524	84634
HPRD ID		02858	09167
Ensembl ID		ENSG00000119383	ENSG00000116014
Uniprot IDs		F6WIT2 Q15257	Q969F8
PDB IDs		2G62 2HV6 2HV7 2IXM 4LAC 4NY3	7YQE 8XGO 8XGS 8XGU 8ZJD 8ZJE
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Cycle Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Intracellular Signal Transduction Positive Regulation Of Cell Communication Regulation Of Signal Transduction Positive Regulation Of Signaling Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Cytoplasm Regulation Of Intracellular Signal Transduction Negative Regulation Of Cell Communication Regulation Of Wnt Signaling Pathway TOR Signaling Positive Regulation Of Signal Transduction Regulation Of Apoptotic Signaling Pathway Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition Cellular Response To Nerve Growth Factor Stimulus Positive Regulation Of Protein Localization Response To Nerve Growth Factor Positive Regulation Of Cell Cycle Signal Transduction Regulation Of Mitotic Cell Cycle Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Mitotic Cell Cycle Regulation Of Generation Of Precursor Metabolites And Energy Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Biosynthetic Process Regulation Of Canonical Wnt Signaling Pathway Enzyme Binding Mitotic Cell Cycle Phase Transition Negative Regulation Of Intracellular Signal Transduction Regulation Of TOR Signaling Regulation Of Protein Localization To Nucleus Regulation Of Developmental Process Negative Regulation Of Metabolic Process Regulation Of Cell Motility Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Wnt Signaling Pathway Protein Kinase Binding Regulation Of Locomotion Positive Regulation Of Developmental Process Positive Regulation Of TOR Signaling Mitochondrion Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Negative Regulation Of TOR Signaling Response To Growth Factor	Protein Phosphatase Type 2A Complex Kisspeptin Receptor Binding RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity Phosphoprotein Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Positive Regulation Of Luteinizing Hormone Secretion Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress Protein Tyrosine Phosphatase Activator Activity Phosphatase Activator Activity Protein Serine/threonine Phosphatase Complex Peptidyl-threonine Dephosphorylation ATPase Complex INTAC Complex Vascular Endothelial Cell Response To Fluid Shear Stress GABA Receptor Binding FAR/SIN/STRIPAK Complex Negative Regulation Of Glycolytic Process Response To Lead Ion RNA Polymerase II Transcription Initiation Surveillance Negative Regulation Of Hippo Signaling Negative Regulation Of ATP Metabolic Process Calcium Channel Complex Protein Phosphatase 2A Binding Positive Regulation Of NLRP3 Inflammasome Complex Assembly Cellular Response To Fluid Shear Stress T Cell Homeostasis Peptidyl-prolyl Cis-trans Isomerase Activity Nuclear RNA Surveillance RNA Surveillance Protein Phosphatase Regulator Activity Regulation Of Hippo Signaling Transcription Elongation By RNA Polymerase II Response To Fluid Shear Stress Negative Regulation Of Epithelial To Mesenchymal Transition Tau Protein Binding Regulation Of NLRP3 Inflammasome Complex Assembly Cytoskeleton Organization Regulation Of Glycolytic Process DNA-templated Transcription Elongation Phosphatase Binding Mesoderm Development Lymphocyte Homeostasis Regulation Of Microtubule Polymerization Regulation Of Carbohydrate Catabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?