H1-10 and PLXND1

		H1-10	PLXND1
Description		H1.10 linker histone	plexin D1
Image
GO Annotations	Cellular Component	Nucleosome Nucleus Nucleoplasm Chromosome Nucleolus	Semaphorin Receptor Complex Plasma Membrane Membrane Lamellipodium Axon Lamellipodium Membrane Cell Projection Cell Body Glutamatergic Synapse Plasma Membrane Bounded Cell Projection
	Molecular Function	DNA Binding Double-stranded DNA Binding RNA Binding Structural Constituent Of Chromatin Nucleosomal DNA Binding Cadherin Binding	Protein Binding Semaphorin Receptor Activity Protein Domain Specific Binding
	Biological Process	Nucleosome Assembly Chromosome Condensation Negative Regulation Of DNA Recombination	Angiogenesis Branching Involved In Blood Vessel Morphogenesis Kidney Development Outflow Tract Morphogenesis Cardiac Septum Development Negative Regulation Of Cell Adhesion Synapse Assembly Synaptic Target Recognition Regulation Of Cell Shape Regulation Of Cell Migration Aorta Development Negative Regulation Of Neuron Apoptotic Process Endothelial Cell Migration Regulation Of Angiogenesis Positive Regulation Of Axonogenesis Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Coronary Vasculature Development Semaphorin-plexin Signaling Pathway
Pathways			Other semaphorin interactions NOTCH3 Intracellular Domain Regulates Transcription RND2 GTPase cycle
Drugs
Diseases
GWAS			A body shape index ( 34021172) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 25673412 34021172) Hip index ( 34021172) Low density lipoprotein cholesterol levels ( 32154731) Mean platelet volume ( 32888494) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500 25673412)
Interacting Genes		3 interacting genes: CDC42 IL7R XBP1	3 interacting genes: HOXB5 MACF1 SEMA4A
Entrez ID		8971	23129
HPRD ID		04151	05046
Ensembl ID		ENSG00000184897	ENSG00000004399
Uniprot IDs		Q92522	Q9Y4D7
PDB IDs		2LSO 6L9Z 7K60 7K63 8YTI	3H6N
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Adhesion Regulation Of Cell Adhesion Glutamatergic Synapse GBD Domain Binding Storage Vacuole Phagocytic Vesicle G Protein Activity Positive Regulation Of Cell Development Interleukin-7 Receptor Activity Epithelial Cell Maturation Involved In Salivary Gland Development Positive Regulation Of Lactation Negative Regulation Of Intralumenal Vesicle Formation Epidermal Growth Factor Catabolic Process Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Synaptic Vesicle Recycling Via Endosome Synaptic Target Recognition Positive Regulation Of T Cell Differentiation Endothelin Receptor Signaling Pathway Involved In Heart Process Cellular Homeostasis Positive Regulation Of Lymphocyte Differentiation Response To Insulin-like Growth Factor Stimulus Regulation Of Lactation Lipophagy Medium-chain Fatty Acyl-CoA Dehydrogenase Activity Leading Edge Membrane Thioesterase Binding Positive Regulation Of Cell Population Proliferation Positive Regulation Of Pinocytosis Regulation Of Cell Migration Apolipoprotein A-I Receptor Binding Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Transport Positive Regulation Of Epithelial Cell Proliferation Cell Junction Assembly Neuron Fate Determination Cell Surface Receptor Signaling Pathway Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Establishment Of Golgi Localization Establishment Of Organelle Localization Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Neuropilin Signaling Pathway Golgi Transport Complex Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Negative Regulation Of T Cell Mediated Cytotoxicity Interleukin-7-mediated Signaling Pathway Positive Regulation Of T Cell Activation Regulation Of Cell Development Regulation Of Lymphocyte Differentiation Negative Regulation Of Programmed Cell Death
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?