PLXND1 and ISY1

  • Data Source: HiPPIP (Novel)

PLXND1

ISY1

Name plexin D1 ISY1 spliceosome associated protein
Structure PDB 3H6N PDB 5YZG
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
GWAS
  • A body shape index ( 34021172 )
  • Hip circumference ( 25673412 )
  • Hip circumference adjusted for BMI ( 25673412 34021172 )
  • Hip index ( 34021172 )
  • Low density lipoprotein cholesterol levels ( 32154731 )
  • Mean platelet volume ( 32888494 )
  • Waist circumference adjusted for body mass index ( 34021172 )
  • Waist-hip index ( 34021172 )
  • Waist-hip ratio ( 25673412 )
  • Waist-to-hip ratio adjusted for BMI ( 34021172 26426971 )
  • Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226 )
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625 )
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971 )
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500 )
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500 )
  • Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971 )
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )
  • Waist-to-hip ratio adjusted for body mass index ( 28448500 25673412 )
  • Waist-to-hip ratio adjusted for BMI ( 26426971 )
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971 )
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )
Novel Interactors 5 novel interactors: H1-10 ISY1 PODXL2 SEC61A1 TMCC1 2 novel interactors: ACAD9 PLXND1
Interacting Genes 3 interacting genes: HOXB5 MACF1 SEMA4A 9 interacting genes: CCNC EXOC8 FAM90A1 KDM8 LMO1 LMO2 MLH1 PTBP2 WBP4
Entrez ID 23129 57461
HPRD ID 05046 13834
Ensembl ID ENSG00000004399 ENSG00000240682
Uniprot IDs Q9Y4D7 Q9ULR0
PDB IDs 3H6N 5YZG 6FF7 6ZYM 7A5P 8C6J 8CH6 8I0W 8RO2 9FMD