PLXND1

Description		plexin D1
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GO Annotations	Cellular Component	Semaphorin Receptor Complex Plasma Membrane Membrane Lamellipodium Axon Lamellipodium Membrane Cell Projection Cell Body Glutamatergic Synapse Plasma Membrane Bounded Cell Projection
	Molecular Function	Protein Binding Semaphorin Receptor Activity Protein Domain Specific Binding
	Biological Process	Angiogenesis Branching Involved In Blood Vessel Morphogenesis Kidney Development Outflow Tract Morphogenesis Cardiac Septum Development Negative Regulation Of Cell Adhesion Synapse Assembly Synaptic Target Recognition Regulation Of Cell Shape Regulation Of Cell Migration Aorta Development Negative Regulation Of Neuron Apoptotic Process Endothelial Cell Migration Regulation Of Angiogenesis Positive Regulation Of Axonogenesis Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Coronary Vasculature Development Semaphorin-plexin Signaling Pathway
Pathways		Other semaphorin interactions NOTCH3 Intracellular Domain Regulates Transcription RND2 GTPase cycle
Drugs
Diseases
GWAS		A body shape index ( 34021172) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 25673412 34021172) Hip index ( 34021172) Low density lipoprotein cholesterol levels ( 32154731) Mean platelet volume ( 32888494) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500 25673412)
Novel Interacting Genes		5 novel interacting genes: H1-10 ISY1 PODXL2 SEC61A1 TMCC1
Interacting Genes		3 interacting genes: HOXB5 MACF1 SEMA4A
Entrez ID		23129
HPRD ID		05046
Ensembl ID		ENSG00000004399
Uniprot IDs		Q9Y4D7
PDB IDs		3H6N
Enriched GO Terms of Interacting Partners?
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