PLXND1

Gene Name		plexin D1
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Gene Ontology Annotations	Cellular Component	Intracellular Plasma Membrane Integral Component Of Plasma Membrane Lamellipodium
	Molecular Function	Protein Binding Semaphorin Receptor Activity Protein Domain Specific Binding
	Biological Process	Angiogenesis Patterning Of Blood Vessels Outflow Tract Morphogenesis Axon Guidance Synapse Assembly Regulation Of Cell Migration Positive Regulation Of Protein Binding Endothelial Cell Migration Regulation Of Angiogenesis Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Semaphorin-plexin Signaling Pathway
Pathways		Axon guidance Semaphorin interactions Other semaphorin interactions
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: MACF1 SEMA4A
Entrez ID		23129
HPRD ID		05046
Ensembl ID		ENSG00000004399
Uniprot IDs		Q9Y4D7
PDB IDs		3H6N
Enriched GO Terms of Interacting Partners?		Regulation Of Epithelial Cell Migration Regulation Of Cell Morphogenesis Posttranslational Protein Targeting To Membrane Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Cellular Component Movement T-helper 1 Cell Differentiation Golgi To Plasma Membrane Protein Transport Anatomical Structure Formation Involved In Morphogenesis T-helper 1 Type Immune Response T-helper Cell Differentiation Golgi To Plasma Membrane Transport CD4-positive, Alpha-beta T Cell Differentiation CD4-positive, Alpha-beta T Cell Activation Positive Regulation Of Axon Extension Semaphorin-plexin Signaling Pathway Regulation Of Focal Adhesion Assembly Movement Of Cell Or Subcellular Component Generation Of Neurons Alpha-beta T Cell Differentiation Regulation Of Cell Junction Assembly Neurogenesis Alpha-beta T Cell Activation T Cell Activation Involved In Immune Response Regulation Of Axon Extension Positive Regulation Of Axonogenesis Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Angiogenesis Regulation Of Cellular Component Organization Post-Golgi Vesicle-mediated Transport Mesoderm Formation Mesoderm Morphogenesis Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Endothelial Cell Migration Nervous System Development Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell Growth Protein Localization To Endoplasmic Reticulum Anatomical Structure Morphogenesis Formation Of Primary Germ Layer Regulation Of Cell Size Cell Cycle Arrest Mesoderm Development Protein Localization To Plasma Membrane T Cell Differentiation Leukocyte Activation Involved In Immune Response Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Developmental Growth
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