H1-10

Name	H1.10 linker histone
Structure
Novel Interactors	3 novel interactors: ACAD9 PLXND1 RAB7A
Interactors	3 interactors: CDC42 IL7R XBP1
GO Annotations	Cellular Component	Nucleosome Nucleus Nucleoplasm Chromosome Nucleolus
	Molecular Function	DNA Binding Double-stranded DNA Binding RNA Binding Structural Constituent Of Chromatin Nucleosomal DNA Binding Cadherin Binding
	Biological Process	Nucleosome Assembly Chromosome Condensation Negative Regulation Of DNA Recombination
GWAS	No GWAS studies recorded
Entrez ID	8971
HPRD ID	04151
Ensembl ID	ENSG00000184897
Uniprot IDs	Q92522
PDB IDs	2LSO 6L9Z 7K60 7K63 8YTI
GO Terms Enriched among Interactors ?	Positive Regulation Of Cell Adhesion Regulation Of Cell Adhesion Glutamatergic Synapse GBD Domain Binding Storage Vacuole Phagocytic Vesicle G Protein Activity Positive Regulation Of Cell Development Interleukin-7 Receptor Activity Epithelial Cell Maturation Involved In Salivary Gland Development Positive Regulation Of Lactation Negative Regulation Of Intralumenal Vesicle Formation Epidermal Growth Factor Catabolic Process Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Synaptic Vesicle Recycling Via Endosome Synaptic Target Recognition Positive Regulation Of T Cell Differentiation Endothelin Receptor Signaling Pathway Involved In Heart Process Cellular Homeostasis Positive Regulation Of Lymphocyte Differentiation Response To Insulin-like Growth Factor Stimulus Regulation Of Lactation Lipophagy Medium-chain Fatty Acyl-CoA Dehydrogenase Activity Leading Edge Membrane Thioesterase Binding Positive Regulation Of Cell Population Proliferation Positive Regulation Of Pinocytosis Regulation Of Cell Migration Apolipoprotein A-I Receptor Binding Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Transport Positive Regulation Of Epithelial Cell Proliferation Cell Junction Assembly Neuron Fate Determination Cell Surface Receptor Signaling Pathway Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Establishment Of Golgi Localization Establishment Of Organelle Localization Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Neuropilin Signaling Pathway Golgi Transport Complex Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Negative Regulation Of T Cell Mediated Cytotoxicity Interleukin-7-mediated Signaling Pathway Positive Regulation Of T Cell Activation Regulation Of Cell Development Regulation Of Lymphocyte Differentiation Negative Regulation Of Programmed Cell Death