MAF1

Description		MAF1 negative regulator of RNA polymerase III
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Axon Dendrite Perinuclear Region Of Cytoplasm Inhibitory Synapse
	Molecular Function	RNA Polymerase III Core Binding RNA Polymerase III Type 1 Promoter Sequence-specific DNA Binding RNA Polymerase III Type 2 Promoter Sequence-specific DNA Binding RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Protein Binding GABA Receptor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase I Negative Regulation Of Transcription By RNA Polymerase III
Pathways		Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases
GWAS		Asthma ( 31959851 32296059) Serum metabolite concentrations in chronic kidney disease ( 33838163)
Interacting Genes		9 interacting genes: CCND3 CDKN2A CSNK2A1 CSNK2A2 DDIAS LAMTOR5 MTOR NUDT3 SUMO2
Entrez ID		84232
HPRD ID		14345
Ensembl ID		ENSG00000179632
Uniprot IDs		Q9H063
PDB IDs		3NR5
Enriched GO Terms of Interacting Partners?		Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Proteolysis Negative Regulation Of Proteolysis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Kinase CK2 Complex Regulation Of Proteasomal Protein Catabolic Process Regulation Of Apoptotic Process Negative Regulation Of Catabolic Process Regulation Of Programmed Cell Death Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Protein Catabolic Process PML Body Negative Regulation Of Apoptotic Process Apoptotic Process SUMO Transferase Activity Programmed Cell Death Cell Death Negative Regulation Of Programmed Cell Death RNA Decapping Regulation Of Protein Localization To Nucleus PcG Protein Complex Regulation Of Cell Cycle Regulation Of Cellular Response To Stress Regulation Of Macroautophagy Positive Regulation Of Protein Catabolic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of Apoptotic Signaling Pathway Protein Stabilization Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Translational Initiation Protein Sumoylation Regulation Of Cell Cycle Process Autophagy Protein Destabilization Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Ligase Inhibitor Activity Negative Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of TORC1 Signaling TORC1 Signaling Positive Regulation Of SCF-dependent Proteasomal Ubiquitin-dependent Catabolic Process Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity Diphosphoinositol Polyphosphate Catabolic Process Protein Serine Kinase Activity Regulation Of Chromosome Separation Regulation Of Protein Stability
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