MAF1 and DDIAS

Number of citations of the paper that reports this interaction (PubMedID 28079882)
30

Data Source:
BioGRID (two hybrid)

		MAF1	DDIAS
Description		MAF1 negative regulator of RNA polymerase III	DNA damage induced apoptosis suppressor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Axon Dendrite Perinuclear Region Of Cytoplasm Inhibitory Synapse	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase III Core Binding RNA Polymerase III Type 1 Promoter Sequence-specific DNA Binding RNA Polymerase III Type 2 Promoter Sequence-specific DNA Binding RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Protein Binding GABA Receptor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase I Negative Regulation Of Transcription By RNA Polymerase III	Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Cell Cycle Regulation Of DNA Stability Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways		Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases
GWAS		Asthma ( 31959851 32296059) Serum metabolite concentrations in chronic kidney disease ( 33838163)
Interacting Genes		9 interacting genes: CCND3 CDKN2A CSNK2A1 CSNK2A2 DDIAS LAMTOR5 MTOR NUDT3 SUMO2	10 interacting genes: ACLY ACTN1 ACTN4 CBY1 ECM1 EFEMP1 FBLN1 MAF1 MIF4GD PLSCR1
Entrez ID		84232	220042
HPRD ID		14345	08062
Ensembl ID		ENSG00000179632	ENSG00000165490
Uniprot IDs		Q9H063	B4DMA1 Q8IXT1
PDB IDs		3NR5
Enriched GO Terms of Interacting Partners?		Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Proteolysis Negative Regulation Of Proteolysis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Kinase CK2 Complex Regulation Of Proteasomal Protein Catabolic Process Regulation Of Apoptotic Process Negative Regulation Of Catabolic Process Regulation Of Programmed Cell Death Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Protein Catabolic Process PML Body Negative Regulation Of Apoptotic Process Apoptotic Process SUMO Transferase Activity Programmed Cell Death Cell Death Negative Regulation Of Programmed Cell Death RNA Decapping Regulation Of Protein Localization To Nucleus PcG Protein Complex Regulation Of Cell Cycle Regulation Of Cellular Response To Stress Regulation Of Macroautophagy Positive Regulation Of Protein Catabolic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of Apoptotic Signaling Pathway Protein Stabilization Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Translational Initiation Protein Sumoylation Regulation Of Cell Cycle Process Autophagy Protein Destabilization Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Ligase Inhibitor Activity Negative Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of TORC1 Signaling TORC1 Signaling Positive Regulation Of SCF-dependent Proteasomal Ubiquitin-dependent Catabolic Process Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity Diphosphoinositol Polyphosphate Catabolic Process Protein Serine Kinase Activity Regulation Of Chromosome Separation Regulation Of Protein Stability	Extracellular Exosome Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Calcium Ion Binding Pseudopodium Extracellular Matrix Structural Constituent Regulation Of Macromolecule Biosynthetic Process Integrin Binding Regulation Of Gene Expression Regulation Of Primary Metabolic Process Epidermal Growth Factor Receptor Binding Regulation Of Macromolecule Metabolic Process ATP Citrate Synthase Activity Extracellular Region Regulation Of DNA-templated Transcription Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of RNA Biosynthetic Process Cortical Actin Cytoskeleton Regulation Of Metabolic Process Negative Regulation Of Cell-substrate Adhesion RNA Polymerase III Core Binding Platelet Alpha Granule Lumen Platelet Activation Extracellular Space Regulation Of RNA Metabolic Process Acyltransferase Activity, Acyl Groups Converted Into Alkyl On Transfer Nucleoside Binding Regulation Of Nucleobase-containing Compound Metabolic Process Muscle Cell Development Positive Regulation Of Sodium:proton Antiporter Activity Stress Fiber Platelet Morphogenesis Structural Constituent Of Postsynapse Extracellular Matrix Regulation Of Transformation Of Host Cell By Virus Negative Regulation Of Transformation Of Host Cell By Virus Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate Epidermal Growth Factor Receptor Activity Phosphatidylserine Biosynthetic Process Mercury Ion Binding Lead Ion Binding Phosphatidylserine Exposure On Apoptotic Cell Surface Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Histone MRNA Stem-loop Binding Complex RNA Polymerase III Type 1 Promoter Sequence-specific DNA Binding RNA Polymerase III Type 2 Promoter Sequence-specific DNA Binding Identical Protein Binding Citrate Metabolic Process Negative Regulation Of Transcription By RNA Polymerase III Z Disc Transmembrane Transporter Binding
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