FUBP3 and MARCHF8

Number of citations: 48 (PubMedID 35695513)
Data Source: BioGRID (pull down)

		FUBP3	MARCHF8
Name		far upstream element binding protein 3	membrane associated ring-CH-type finger 8
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Ribosome Membrane Neuronal Cell Body Dendritic Shaft	Golgi Membrane Cytoplasm Lysosome Lysosomal Membrane Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Late Endosome Membrane
	Molecular Function	Nucleic Acid Binding DNA Binding Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity MHC Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Intracellular MRNA Localization Positive Regulation Of Gene Expression Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Protein Polyubiquitination Adaptive Immune Response Immune System Process Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Immune Response Protein Ubiquitination
GWAS		Anthropometric traits ( 30166351 ) Anthropometric traits (multi-trait analysis) ( 30166351 ) Appendicular lean mass ( 33097823 ) Bone mineral density (paediatric, lower limb) ( 24945404 ) Bone mineral density (paediatric, total body less head) ( 24945404 ) Estimated glomerular filtration rate ( 31152163 ) Femoral neck bone mineral density ( 22504420 29499414 ) Fractures ( 30158200 ) Height ( 18391950 20881960 23563607 25282103 28552196 31562340 ) Serum alkaline phosphatase levels ( 33547301 )	No GWAS studies recorded
Interacting Genes		14 interacting genes: APP ATXN1 CALCOCO2 CEBPA LINC00624 MARCHF8 OGT PAX9 PTEN QKI RBPMS2 RNF10 SSX1 XBP1	16 interacting genes: ARR3 CD86 CGAS CYB5B FA2H FUBP3 GOSR2 HNRNPA1 HNRNPK IL1RAP TMEM14C UBC UBE2D1 UBE2D3 UBE2H VAMP2
Entrez ID		8939	220972
HPRD ID		04640	17466
Ensembl ID		ENSG00000107164	ENSG00000165406
Uniprot IDs		Q96I24	Q5T0T0
PDB IDs		Not available	2D8S
GO Terms Enriched among Interactors		Positive Regulation Of Proteolysis Positive Regulation Of RNA Biosynthetic Process Regulation Of Developmental Process Positive Regulation Of RNA Metabolic Process Regulation Of Nervous System Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Catabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Developmental Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Differentiation Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Proteolysis Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cell Differentiation Regulation Of DNA-templated Transcription Developmental Maturation Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Development Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Chromatin DNA Binding Positive Regulation Of Metabolic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Cell Development Learning Or Memory Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Metabolic Process Regulation Of Gliogenesis Positive Regulation Of Lipid Biosynthetic Process Cognition Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Myelination Regulation Of Macromolecule Biosynthetic Process Memory Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Regulation Of Cell Population Proliferation Regulation Of Primary Metabolic Process Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process	Ubiquitin Conjugating Enzyme Activity Protein K48-linked Ubiquitination